Effect of large-scale social marketing of insecticide-treated nets on child survival in rural Tanzania (Publications)
area rose from less than 10% at baseline to more than 50% 3 years later. Insecticide-treated nets were associated with a 27% increase in survival in children aged 1 month to 4 years (95% CI 3-45). Coverage [...] survival was assessed by a case-control approach. Cases were deaths in children aged between 1 month and 4 years. Four controls for each case were chosen from the DSS database. Use of insecticide-treated nets [...] districts (18% in children younger than 5 years) suggests that...
Assessment of the novel T-cell activation marker-tuberculosis assay for diagnosis of active tuberculosis in children: a prospective proof-of-concept... (Publications)
Research Center in Mbeya, and the Ifakara Health Institute in Bagamoyo, Tanzania, between May 10, 2011, and Sept 4, 2012. Sputum and peripheral blood mononuclear cells were obtained for Mycobacterium tuberculosis [...] FINDINGS: Among 290 children screened, we selected a subgroup of 130 to ensure testing of at least 20 with culture-confirmed tuberculosis. 17 of 130 children were excluded because of inconclusive TAM-TB [...] TAM-TB assay enabled detection of 15 of 18 culture-confirmed cases...
Validation of a human-serum-based <em>in vitro </em>growth method for drug screening on juvenile development stages of <em>Schistosoma mansoni</em> (Publications)
developed S. mansoni in Hybridoma medium supplemented with 20% human serum were similar in size as in vivo worms until 28 days of incubation (males 1.4 +/- 0.2 mm, females 1.1 +/- 0.5 mm long). qPCR analysis [...] with the exception of mefloquine, where we observed a 10-fold lower sensitivity on in vitro developed schistosomes when compared to in vivo grown (IC50: 4.43 muM in vitro, 0.48 muM in vivo). CONCLUSION: A
Effect of large-scale social marketing of insecticide-treated nets on child survival in rural Tanzania (Publications)
area rose from less than 10% at baseline to more than 50% 3 years later. Insecticide-treated nets were associated with a 27% increase in survival in children aged 1 month to 4 years (95% CI 3-45). Coverage [...] survival was assessed by a case-control approach. Cases were deaths in children aged between 1 month and 4 years. Four controls for each case were chosen from the DSS database. Use of insecticide-treated nets [...] districts (18% in children younger than 5 years) suggests that...
Assessment of the novel T-cell activation marker-tuberculosis assay for diagnosis of active tuberculosis in children: a prospective proof-of-concept... (Publications)
Research Center in Mbeya, and the Ifakara Health Institute in Bagamoyo, Tanzania, between May 10, 2011, and Sept 4, 2012. Sputum and peripheral blood mononuclear cells were obtained for Mycobacterium tuberculosis [...] FINDINGS: Among 290 children screened, we selected a subgroup of 130 to ensure testing of at least 20 with culture-confirmed tuberculosis. 17 of 130 children were excluded because of inconclusive TAM-TB [...] TAM-TB assay enabled detection of 15 of 18 culture-confirmed cases...
Serological study of <em>Leptospira interrogans</em> serovar Copenhageni and <em>L. borgpetersenii</em> serovars Tarassovi and Ballum in beef cattle,... (Publications)
7 (95% CI=11.7-16.0)%, 12.6 (95 CI=10.6-14.7)% and 18.0 (95% CI=15.7-20.5)% for beef cattle, 10.5 (95% CI=9.0-12.1)%, 16.7 (95% CI=14.9-18.6)% and 14.0 (95% CI=12.4-15.8)% for sheep and 6.6 (95% CI=5.3-8 [...] 29.6% for beef cattle and 73.8, 57.4 and 41.0% for deer, and for Tarassovi, 80.5, 59.7 and 45.1% for sheep, 83.3, 68.5 and 61.1% for beef cattle, and 42.6, 16.4 and 4.9% for deer. Seropositivity to all [...] 3-8.2)%, 15.5 (95% CI=13.5-17.7)% and 3.6 (95% CI=2.7-4.8)% for deer,...
Serological study of <em>Leptospira interrogans</em> serovar Copenhageni and <em>L. borgpetersenii</em> serovars Tarassovi and Ballum in beef cattle,... (Publications)
7 (95% CI=11.7-16.0)%, 12.6 (95 CI=10.6-14.7)% and 18.0 (95% CI=15.7-20.5)% for beef cattle, 10.5 (95% CI=9.0-12.1)%, 16.7 (95% CI=14.9-18.6)% and 14.0 (95% CI=12.4-15.8)% for sheep and 6.6 (95% CI=5.3-8 [...] 29.6% for beef cattle and 73.8, 57.4 and 41.0% for deer, and for Tarassovi, 80.5, 59.7 and 45.1% for sheep, 83.3, 68.5 and 61.1% for beef cattle, and 42.6, 16.4 and 4.9% for deer. Seropositivity to all [...] 3-8.2)%, 15.5 (95% CI=13.5-17.7)% and 3.6 (95% CI=2.7-4.8)% for deer,...
exposure. "Our study showed that transportation noise increases the risk for a heart attack by 2.0 to 3.4% per 10 decibels increase in the average sound pressure level at home." said Martin Röösli, Head of [...] n-sphere. The air pollution and the transportation noise models were applied for each address of the 4.4 million Swiss adult citizen (aged 30 years and above). About the study Héritier H et al. A systematic [...] only included fine particulates (PM 2.5 ) suggest that the risk for a heart...
Anthelmintic activity of medicinal plants used in Côte d'Ivoire for treating parasitic diseases (Publications)
values of 20-200 mug/ml 48 h post-incubation, and 15.4% paralysed adult H. bakeri at 200 mug/ml 72 h after incubation. Of the extracts, 19% resulted in death of adult T. muris at MLC values of 10-100 mug/ml [...] extracts tested (15.4%) in vitro revealed activity against all helminths tested. Of 65 extracts tested in vitro at a concentration of 2 mg/ml, all caused death of schistosomula and 34.4% and 39.1% were lethal
Anthelmintic activity of medicinal plants used in Côte d'Ivoire for treating parasitic diseases (Publications)
values of 20-200 mug/ml 48 h post-incubation, and 15.4% paralysed adult H. bakeri at 200 mug/ml 72 h after incubation. Of the extracts, 19% resulted in death of adult T. muris at MLC values of 10-100 mug/ml [...] extracts tested (15.4%) in vitro revealed activity against all helminths tested. Of 65 extracts tested in vitro at a concentration of 2 mg/ml, all caused death of schistosomula and 34.4% and 39.1% were lethal
