Association of pesticide exposure with neurobehavioral outcomes among avocado farmworkers in Mexico (Publications)
association of urinary pesticide metabolites with higher anxiety (IRR = 1.72, 95% CrI: 1.12, 2.55), depression (IRR = 4.60, 95% CrI: 2.19, 9.43), and GSI (IRR = 1.99, 95% CrI: 1.39, 2.79) scores. OH-TEB and [...] fungicide, or herbicide metabolites measured in urine samples collected during two study visits (8-10 weeks apart). We assessed participants' cognitive function and psychological distress using the NIH
Association of pesticide exposure with neurobehavioral outcomes among avocado farmworkers in Mexico (Publications)
association of urinary pesticide metabolites with higher anxiety (IRR = 1.72, 95% CrI: 1.12, 2.55), depression (IRR = 4.60, 95% CrI: 2.19, 9.43), and GSI (IRR = 1.99, 95% CrI: 1.39, 2.79) scores. OH-TEB and [...] fungicide, or herbicide metabolites measured in urine samples collected during two study visits (8-10 weeks apart). We assessed participants' cognitive function and psychological distress using the NIH
Associations between air pollution and socioeconomic characteristics, ethnicity and age profile of neighbourhoods in England and the Netherlands (Publications)
ns in the most deprived 20% of neighbourhoods in England (1.5 µg/m(3) higher PM10 and 4.4 µg/m(3) NO2). Concentrations in both countries were higher in neighbourhoods with > 20% non-White (England: 3.0 [...] 0 µg/m(3) higher PM10 and 10.1 µg/m(3) NO2; the Netherlands: 1.1 µg/m(3) higher PM10 and 4.5 µg/m(3) NO2) after adjustment for urbanisation and other variables. Associations for some areas differed from [...] at national, regional and city level in England and the Netherlands comparing...
Associations between air pollution and socioeconomic characteristics, ethnicity and age profile of neighbourhoods in England and the Netherlands (Publications)
ns in the most deprived 20% of neighbourhoods in England (1.5 µg/m(3) higher PM10 and 4.4 µg/m(3) NO2). Concentrations in both countries were higher in neighbourhoods with > 20% non-White (England: 3.0 [...] 0 µg/m(3) higher PM10 and 10.1 µg/m(3) NO2; the Netherlands: 1.1 µg/m(3) higher PM10 and 4.5 µg/m(3) NO2) after adjustment for urbanisation and other variables. Associations for some areas differed from [...] at national, regional and city level in England and the Netherlands comparing...
Prevalence of asthma-like symptoms with ageing (Publications)
95% CI 3.0 to 4.2; 2.7%, 95% CI 1.7 to 3.7). Changes were similar in the first 10 years compared with the second 10 years, except for hay fever/nasal allergies (increase seen in the first 10 years only) [...] asthma-like symptoms from representative samples of adults aged 20-44 years (29 centres in 13 European countries and Australia) at baseline and 10 and 20 years later (n=7844). Net changes in symptom prevalence [...] centre level estimates. FINDINGS: Over 20 years the prevalence of 'wheeze'...
Prevalence of asthma-like symptoms with ageing (Publications)
95% CI 3.0 to 4.2; 2.7%, 95% CI 1.7 to 3.7). Changes were similar in the first 10 years compared with the second 10 years, except for hay fever/nasal allergies (increase seen in the first 10 years only) [...] asthma-like symptoms from representative samples of adults aged 20-44 years (29 centres in 13 European countries and Australia) at baseline and 10 and 20 years later (n=7844). Net changes in symptom prevalence [...] centre level estimates. FINDINGS: Over 20 years the prevalence of 'wheeze'...
Antiprotozoal sesquiterpene lactones and other constituents from <em>Tarchonanthus camphoratus</em> and <em>Schkuhria pinnata</em> (Publications)
and 2) from T. camphoratus and 20 known compounds of this type from S. pinnata. From the latter, a new eudesmanolide, (1R*,5S*,6R*,7R*,8R*,10R*)-1-hydroxy-8-[5''-hydroxy-4'-(2''-hydroxyisovaleroyloxy ) [...] (14) and 1(10)-epoxy-3beta-hydroxy-8beta-[5'-hydroxy-4'-(2''-hydroxyisovaleroyloxy)tigloyl oxy]costunolide (16), were obtained. Additionally, the flavonoid pectolinarigenin (24) and 3-hydroxy-4,5-dimeth [...] compounds found in this study, with...
Antiprotozoal sesquiterpene lactones and other constituents from <em>Tarchonanthus camphoratus</em> and <em>Schkuhria pinnata</em> (Publications)
and 2) from T. camphoratus and 20 known compounds of this type from S. pinnata. From the latter, a new eudesmanolide, (1R*,5S*,6R*,7R*,8R*,10R*)-1-hydroxy-8-[5''-hydroxy-4'-(2''-hydroxyisovaleroyloxy ) [...] (14) and 1(10)-epoxy-3beta-hydroxy-8beta-[5'-hydroxy-4'-(2''-hydroxyisovaleroyloxy)tigloyl oxy]costunolide (16), were obtained. Additionally, the flavonoid pectolinarigenin (24) and 3-hydroxy-4,5-dimeth [...] compounds found in this study, with...
Genome-wide association study identifies five loci associated with lung function (Publications)
locus at 4q31 and identified associations with FEV(1) or FEV(1)/FVC and common variants at five additional loci: 2q35 in TNS1 (P = 1.11 x 10(-12)), 4q24 in GSTCD (2.18 x 10(-23)), 5q33 in HTR4 (P = 4.29 x [...] x 10(-9)), 6p21 in AGER (P = 3.07 x 10(-15)) and 15q23 in THSD4 (P = 7.24 x 10(-15)). mRNA analyses showed expression of TNS1, GSTCD, AGER, HTR4 and THSD4 in human lung tissue. These associations offer [...] s (FEV(1)) and the ratio of FEV(1) to forced vital capacity (FVC) in the...
Genome-wide association study identifies five loci associated with lung function (Publications)
locus at 4q31 and identified associations with FEV(1) or FEV(1)/FVC and common variants at five additional loci: 2q35 in TNS1 (P = 1.11 x 10(-12)), 4q24 in GSTCD (2.18 x 10(-23)), 5q33 in HTR4 (P = 4.29 x [...] x 10(-9)), 6p21 in AGER (P = 3.07 x 10(-15)) and 15q23 in THSD4 (P = 7.24 x 10(-15)). mRNA analyses showed expression of TNS1, GSTCD, AGER, HTR4 and THSD4 in human lung tissue. These associations offer [...] s (FEV(1)) and the ratio of FEV(1) to forced vital capacity (FVC) in the...
