Global burden of human food-borne trematodiasis: a systematic review and meta-analysis (Publications)
trematodiases are a group of neglected tropical diseases caused by liver, lung, and intestinal parasitic fluke infections. As part of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD [...] 1980, and Dec 31, 2008. We used a broad search strategy with a combination of search terms and parasite and disease names. The initial search results were then screened on the basis of title, abstract [...] epidemiological disease parameters and methodological features for estimating the...
Very high carriage of gametocytes in asymptomatic low-density <em>Plasmodium falciparum</em> and <em>P. vivax</em> infections in western Thailand (Publications)
pfs25 transcripts was strongly dependent on parasite density. pvs25 transcript numbers, a measure of gametocyte density, were also highly correlated with parasite density (r 2 = 0.82, P < 0.001). CONCLUSIONS: [...] Kanchanaburi and Ratchaburi provinces of Thailand in 2012. The presence of P. falciparum and P. vivax parasites was determined using 18S rRNA qPCR. Gametocytes were also detected by pfs25 / pvs25 qRT-PCRs. RESULTS:
Schistosomes, snails and climate change: current trends and future expectations (Publications)
mainly in tropical and subtropical countries, is currently unknown, but likely to vary with the snail-parasite species' specific ecologies and the spatio-temporal scale of investigation. Here, by means of a [...] associated with climate change responses were found to be variable across geographical regions and snail-parasite taxonomic groups. Indeed, the strongest evidence stems from the People's Republic of China pertaining [...] temperatures. The consequences for schistosomiasis...
Toxocariasis-associated cardiac diseases: a systematic review of the literature (Publications)
Toxocariasis, caused by Toxocara canis or Toxocara catis, is a worldwide occurring parasitic disease, reaching high prevalences especially in tropical and subtropical countries. The clinical presentation [...] histological analysis was performed (either pre- or post-mortem), granulomas or remnants of the parasite were detected. In the other six cases, findings were non-specific; the damage of the heart was equally [...] corticosteroid appears to be a valuable option. For the daily clinical work,...
Reduced Efficacy of Anthelmintic Drugs (News)
https://www.swisstph.ch/en/news/20170926-reduced-efficacy-of-anthelmintic-drugs
soil-transmitted helminths: Ascaris lumbricoides , hookworm and T. trichiura . They are caused by parasitic worms which are transmitted by eggs present in human feces, which contaminate the soil in areas [...] where sanitation is poor. Infected children are physically, nutritionally and cognitively impaired. Parasitic worm infections are a major public health concern among the poor and most vulnerable populations [...] institutions worldwide in discovering novel treatments and conducting...
On a mission to block transmission (Publications)
The controlled infection of volunteers with Plasmodium falciparum parasites could provide a platform to evaluate new drugs and vaccines aimed at blocking malaria transmission.
On a mission to block transmission (Publications)
The controlled infection of volunteers with Plasmodium falciparum parasites could provide a platform to evaluate new drugs and vaccines aimed at blocking malaria transmission.
Antimalarial agents derived from metal-amodiaquine complexes with activity in multiple stages of the plasmodium life cycle (Publications)
bond. Ru(II)- and Au(I)-AQ complexes were demonstrated to be potent and efficacious in inhibiting parasite growth in multiple stages of the Plasmodium life cycle assayed in vitro and in vivo. These properties [...] the suppression of heme detoxification induced by AQ, while also inhibiting other processes in the parasite life cycle, which can be attributed to the action of the metallic species. These findings indicate
Transporters of <em>Trypanosoma brucei</em>: phylogeny, physiology, pharmacology (Publications)
sickness, T. b. gambiense and T. b. rhodesiense, as well as the livestock-pathogenic T. b. brucei. The parasites are transmitted by the tsetse fly and occur exclusively in sub-Saharan Africa. T. brucei are not [...] transport proteins of T. brucei, their contribution to homeostasis and metabolism in the context of a parasitic lifestyle, and their pharmacological role as potential drug targets or routes of drug entry. Tr
Comparative sphingolipidomics of disease-causing trypanosomatids reveal unique lifecycle- and taxonomy-specific lipid chemistries (Publications)
are parasitic protozoa which cause a spectrum of diseases, including trypanosomiasis and leishmaniasis, affecting millions of humans and animals worldwide. The surface of most protozoan parasites is heavily
