Induction of parasite growth-inhibitory antibodies by a virosomal formulation of a peptidomimetic of loop I from domain III of <em>Plasmodium... (Publications)
antibodies which specifically bound to parasite-expressed AMA-1 in Western blotting with parasite lysates as well as in immunofluorescence assays with blood stage parasites. All 11 peptidomimetic-specific monoclonal [...] a virosomal formulation of a peptide that mimics the semiconserved loop I of domain III elicits parasite growth-inhibitory antibodies. A synthetic peptide comprising residues 446 to 490 of AMA-1 (AMA- [...] monoclonal antibodies generated were cross-reactive with parasite-expre...
Helminth parasites and hypobiosis of nematodes in N'Dama cattle during the dry season in The Gambia (Publications)
Three series of necropsies of cattle were performed, corresponding to early dry season, approximately 1 month after the last rains (November, n = 6), mid dry season (February, n = 6) and end dry seaso
Bromopyrrole alkaloids as lead compounds against protozoan parasites (Publications)
marine sponges belonging to Axinella and Agelas genera have been screened in vitro against four parasitic protozoa, i.e., two Trypanosoma species (T. brucei rhodesiense and T. cruzi), Leishmania donovani
Diagnostics are central for a truly holistic approach against intestinal parasitic diseases (Publications)
on the central role of diagnostics for a truly holistic approach against gastrointestinal (GI) parasitic diseases. This article was motivated by a recent review in the International Journal of Infectious
In silico ionomics segregates parasitic from free-living eukaryotes (Publications)
hand, from free-living species and facultative parasites (n=14) on the other hand. This surprising finding indicates strong convergent evolution of the parasites regarding the acquisition and homeostasis of [...] s of iron and other transition metals, as the most informative for distinguishing the obligate parasites. Thus in silico ionomics further underscores the importance of iron in infection biology and suggests [...] access to host sources of nitrogen and transition metals to be selective...
Inhibitory activity of marine sponge-derived natural products against parasitic protozoa (Publications)
well as an indole alkaloid, tryptophol (14) were screened for their in vitro activity against four parasitic protozoa; Trypanosoma brucei rhodesiense, Trypanosoma cruzi, Leishmania donovani and Plasmodium
Water-related parasitic diseases in China (Publications)
considerable burden due to parasitic diseases in certain areas and populations across the country. In this review, we demonstrated three aspects of ten major water-related parasitic diseases, i.e., the biology [...] Water-related parasitic diseases are directly dependent on water bodies for their spread or as a habitat for indispensable intermediate or final hosts. Along with socioeconomic development and improvement
