Searched for parasites.

1. Design, synthesis and evaluation of novel uracil amino acid conjugates for the inhibition of <em>Trypanosoma cruzi </em>dUTPase (Publications)

   Design, synthesis and evaluation of novel uracil amino acid conjugates for the inhibition of <em>Trypanosoma cruzi </em>dUTPase

   Relevance:

   library of amino acid uracil acetamide compounds which were evaluated for enzyme inhibition and anti-parasitic activity

2. <em>Dirofilaria repens</em> infection and concomitant meningoencephalitis (Publications)

   <em>Dirofilaria repens</em> infection and concomitant meningoencephalitis

   Relevance:

   Clinical symptoms are usually restricted to a subcutaneous nodule containing a single infertile parasite. Here, we report a case of D. repens infection with a subcutaneous gravid worm and the patient's

3. Anna K. H. Hirsch: drug design and optimisation to disarm dangerous germs (Publications)

   Anna K. H. Hirsch: drug design and optimisation to disarm dangerous germs

   Relevance:

   dedicated to fighting infectious diseases by focussing on enzymes that are central to the metabolism of parasites. Her research has led to a valuable collaboration with the Swiss Tropical and Public Health Institute

4. Multiparasitism, production and economics in domestic animals in sub-Saharan West Africa (Publications)

   Multiparasitism, production and economics in domestic animals in sub-Saharan West Africa

   Relevance:

   helminthosis network has developed (), with the aims of both improving livestock productivity through parasite control and, ultimately, increasing rural income. The network places a strong emphasis on building

5. The sensitivity of the OptiMAL rapid diagnostic test to the presence of <em>Plasmodium falciparum </em>gametocytes compromises its ability to monitor... (Publications)

   The sensitivity of the OptiMAL rapid diagnostic test to the presence of <em>Plasmodium falciparum </em>gametocytes compromises its ability to monitor treatment outcomes in an area of Papua New Guinea in which malaria is endemic

   Relevance:

   in vivo samples from treatment failure malaria cases, we demonstrate the high sensitivity of the parasite lactase dehydrogenase (pLDH)-based OptiMAL rapid diagnostic test in the detection of P. falciparum

6. Novel inhibitors of leishmanial dihydrofolate reductase (Publications)

   Novel inhibitors of leishmanial dihydrofolate reductase

   Relevance:

   reductase. A number of compounds were obtained and screened against the enzyme and against the intact parasite Leishmania donovani and the related organisms Trypanosoma brucei and Trypanosoma cruzi. The compounds

7. Novel inhibitors of leishmanial dihydrofolate reductase (Publications)

   Novel inhibitors of leishmanial dihydrofolate reductase

   Relevance:

   reductase. A number of compounds were obtained and screened against the enzyme and against the intact parasite Leishmania donovani and the related organisms Trypanosoma brucei and Trypanosoma cruzi. The compounds

8. Multiparasitism, production and economics in domestic animals in sub-Saharan West Africa (Publications)

   Multiparasitism, production and economics in domestic animals in sub-Saharan West Africa

   Relevance:

   helminthosis network has developed (), with the aims of both improving livestock productivity through parasite control and, ultimately, increasing rural income. The network places a strong emphasis on building

9. The sensitivity of the OptiMAL rapid diagnostic test to the presence of <em>Plasmodium falciparum </em>gametocytes compromises its ability to monitor... (Publications)

   The sensitivity of the OptiMAL rapid diagnostic test to the presence of <em>Plasmodium falciparum </em>gametocytes compromises its ability to monitor treatment outcomes in an area of Papua New Guinea in which malaria is endemic

   Relevance:

   in vivo samples from treatment failure malaria cases, we demonstrate the high sensitivity of the parasite lactase dehydrogenase (pLDH)-based OptiMAL rapid diagnostic test in the detection of P. falciparum

10. A novel pyrazolopyridine with<em> in vivo</em> activity in <em>Plasmodium berghei</em>- and <em>Plasmodium falciparum</em>-infected mouse models from... (Publications)

    A novel pyrazolopyridine with<em> in vivo</em> activity in <em>Plasmodium berghei</em>- and <em>Plasmodium falciparum</em>-infected mouse models from structure-activity relationship studies around the core of recently identified antimalarial imidazopyrida

    Relevance:

    efficacy and pharmacokinetics profiles. The lead compounds also proved to be very potent in the parasite liver and gametocyte stages, which makes them of high interest