Effect of insecticide-treated bed nets on the dynamics of multiple <em>Plasmodium falciparum</em> infections (Publications)
intervals of one month indicated that the average duration of infections, allowing for undetected parasite genotypes, was 73 d in those aged < 18 months and 160 d in children aged > or = 18 months, consistent [...] (SE = 6%) compared with 41% (SE = 6%) in older children. Conversely, the rate of appearance of new parasite genotypes was higher in children < 18 months of age than in older children, but this partly reflected
Circulating Anodic Antigen (CAA): a highly sensitive diagnostic biomarker to detect active <em>Schistosoma </em>infections-improvement and use during... (Publications)
larger SCORE studies. For example, in Zanzibar, we demonstrated that urine filtration, the standard parasite egg detection diagnostic test for S. haematobium, greatly underestimated prevalence in low-prevalence [...] antigen (CAA) assay provided critical information about the limitations of the stool-based Kato-Katz parasite egg-detection assay for S. mansoni in low-prevalence settings. Other SCORE-supported CAA work d
Anti-trypanosomatid elemanolide sesquiterpene lactones from<em> Vernonia lasiopus </em>O. Hoffm (Publications)
developed regions of sub-Saharan Africa and is caused by the kinetoplastid "protozoan" parasite Trypanosoma brucei. The parasites are transmitted to humans through bites of infected tsetse flies of the genus Glossina
Persistent digestive disorders in the tropics: causative infectious pathogens and reference diagnostic tests (Publications)
detail. RESULTS: Over 30 pathogens may cause persistent digestive disorders. Bacteria, viruses and parasites are important aetiologic agents of acute and long-lasting symptomatologies. An integrated approach [...] for toxin, antigen and antibody detection, is required for accurate diagnosis of bacteria and parasites. Molecular techniques are essential for sensitive diagnosis of many viruses, bacteria and intestinal
Relative effects of climate factors and malaria control interventions on changes of parasitaemia risk in Burkina Faso from 2014 to 2017/2018 (Publications)
decades, following the scale-up of control interventions. The successful development of malaria parasites depends on several climatic factors. Intervention gains may be reversed by changes in climatic factors [...] effects of malaria control interventions and climatic factors on the temporal changes of malaria parasite prevalence. Additionally, intervention effects were assessed at regional level, using a spatially
Bridging the gap from molecular surveillance to programmatic decisions for malaria control and elimination (Publications)
An increasing number of molecular and genomic assays are available to study malaria parasite populations. However, so far they have played a marginal role in informing policy and programmatic decision-making [...] reaction to monitor the prevalence of sub-patent infections in asymptomatic carriers, monitoring parasite genetic diversity as transmission intensity is changing, using genomic data to determine the origin
Post-Kala-Azar dermal leishmaniasis as a reservoir for visceral leishmaniasis transmission (Publications)
Post-kala-azar dermal leishmaniasis (PKDL) is a parasitic skin infection which can occur after visceral leishmaniasis (VL). Recent xenodiagnosis studies (Mondal et al., Clin. Infect. Dis., 2018) have uncovered
The discovery of helminth life cycles (Publications)
left humans wondering for centuries. The story of the gradual discovery of the life cycles of the parasitic helminths is a fascinating one, peppered with misconceptions, misguided by dogmas of the church
The discovery of helminth life cycles (Publications)
left humans wondering for centuries. The story of the gradual discovery of the life cycles of the parasitic helminths is a fascinating one, peppered with misconceptions, misguided by dogmas of the church
Post-Kala-Azar dermal leishmaniasis as a reservoir for visceral leishmaniasis transmission (Publications)
Post-kala-azar dermal leishmaniasis (PKDL) is a parasitic skin infection which can occur after visceral leishmaniasis (VL). Recent xenodiagnosis studies (Mondal et al., Clin. Infect. Dis., 2018) have uncovered