Fighting schistosomiasis through research and interventions in Pemba, Tanzania (Blog)
https://www.swisstph.ch/en/impact-stories/fighting-schistosomiasis-through-research-and-interventions-in-pemba-tanzania/blog-id/96
have been working together with local partners to tackle schistosomiasis, a disease caused by parasitic worm infections, on Pemba Island. A new documentary offers an in-depth look at this journey, showcasing
Spinal cystic echinococcosis - a systematic analysis and review of the literature: part 1. Epidemiology and anatomy (Publications)
techniques as well as surgical and medical treatment of spinal CE, our basic understanding of the parasite's predilection for the spine remains incomplete. To fill this gap, we systematically reviewed the
Neue Parameter für die Wirkstofftestung gegen <em>Trypanosoma cruzi</em> (Publications)
chronic stage. This is where high-content imaging makes a key contribution: assays with fluorescent parasites in cell culture allow to determine pharmacodynamic parameters and to better assess the antichagasic
Malaria websites (Publications)
post-travel advice and management of travelers with illness upon return, 2) the essential on the parasite, the diagnosis and the treatment, 3) the malaria problem worldwide and 4) malaria maps
Synthetic GPI array to study antitoxic malaria response (Publications)
Parasite glycosylphosphatidylinositol (GPI) is an important toxin in malaria disease, and people living in malaria-endemic regions often produce high levels of anti-GPI antibodies. The natural anti-GPI
[(eta(6) -praziquantel)Cr(CO)(3)] derivatives with remarkable in vitro anti-schistosomal activity (Publications)
available praziquantel. Both derivatives show a high in vitro activity against Schistosoma mansoni, a parasitic trematode, and had only a minor cytotoxic effect on selected mammalian cell lines
Novel synthetic route for antimalarial benzo[a]phenoxazine derivative SSJ-183 and two active metabolites (Publications)
and ?2-fold increased activities against drug-sensitive and drug-resistant Plasmodium falciparum parasites.
In vitro and in vivo treatments of <em>Echinococcus </em>protoscoleces and metacestodes with artemisinin and artemisinin derivatives (Publications)
both drugs with albendazole led to a substantial but statistically not significant reduction in parasite weight compared to results with albendazole alone
3-hydroxy-N'-arylidenepropanehydrazonamides with halo-substituted phenanthrene scaffolds cure <em>P. berghei</em> infected mice when administered... (Publications)
subnanomolar antiplasmodial activity against asexual blood stages of Plasmodium falciparum, excellent parasite selectivity, and nanomolar activity against the earliest forms of gametocyte development. Particularly
Incorporation of an intramolecular hydrogen bonding motif in the side chain of antimalarial benzimidazoles (Publications)
against chloroquine-sensitive (NF54) and multi-drug resistant (K1) strains of the human malaria parasite Plasmodium falciparum. Compounds were also screened for their cytotoxicity towards a mammalian Chinese