<em>Strongyloides stercoralis</em>: spatial distribution of a highly prevalent and ubiquitous soil-transmitted helminth in Cambodia (Publications)
participants with a complete data record was 30.5%, ranging from 10.9% to 48.2% across provinces. The parasite was ubiquitous in Cambodia; only five south-eastern provinces had prevalence rates below 20%. Infection [...] infection is rampant in Cambodia. Control programs delivering ivermectin are needed to manage the parasite. However, the high cost of this drug in Cambodia currently precludes the implementation of control
Haematological consequences of acute uncomplicated <em>falciparum </em>malaria: a WorldWide Antimalarial Resistance Network pooled analysis of... (Publications)
Plasmodium falciparum malaria is associated with anaemia-related morbidity, attributable to host, parasite and drug factors. We quantified the haematological response following treatment of uncomplicated [...] AOR = 6.79, respectively), high parasitaemia (AOR = 1.78 and AOR = 1.58, respectively) and delayed parasite clearance (AOR = 2.44 and AOR = 2.59, respectively). In Asia, patients treated with an artemisinin-based [...] occurs 2 days after starting treatment. Although artemisinin-based...
Diagnostic performance and comparison of ultrasensitive and conventional rapid diagnostic test, thick blood smear and quantitative PCR for detection... (Publications)
Progress towards malaria elimination has stagnated, partly because infections persisting at low parasite densities comprise a large reservoir contributing to ongoing malaria transmission and are difficult [...] and treatment was administered. qPCR was the reference for the presence of Plasmodium falciparum parasites. RESULTS: 279 samples were collected from 24 participants; 123 were positive by qPCR. TBS detected [...] than cRDT (TBS vs. cRDT p = 0.015; uRDT vs. cRDT p = 0.053), detecting...
Diagnostic performance and comparison of ultrasensitive and conventional rapid diagnostic test, thick blood smear and quantitative PCR for detection... (Publications)
Progress towards malaria elimination has stagnated, partly because infections persisting at low parasite densities comprise a large reservoir contributing to ongoing malaria transmission and are difficult [...] and treatment was administered. qPCR was the reference for the presence of Plasmodium falciparum parasites. RESULTS: 279 samples were collected from 24 participants; 123 were positive by qPCR. TBS detected [...] than cRDT (TBS vs. cRDT p = 0.015; uRDT vs. cRDT p = 0.053), detecting...
Haematological consequences of acute uncomplicated <em>falciparum </em>malaria: a WorldWide Antimalarial Resistance Network pooled analysis of... (Publications)
Plasmodium falciparum malaria is associated with anaemia-related morbidity, attributable to host, parasite and drug factors. We quantified the haematological response following treatment of uncomplicated [...] AOR = 6.79, respectively), high parasitaemia (AOR = 1.78 and AOR = 1.58, respectively) and delayed parasite clearance (AOR = 2.44 and AOR = 2.59, respectively). In Asia, patients treated with an artemisinin-based [...] occurs 2 days after starting treatment. Although artemisinin-based...
Never seen before? Opisthorchiasis and Clonorchiasis (Publications)
Parasitic diseases are relatively rarely diagnosed and treated in Europe. Therefore, European clinicians are not familiar with their clinical and imaging features. In an era of increased human migration
Synthesis and biological characterisation of ester and amide derivatives of fusidic acid as antiplasmodial agents (Publications)
activity against the chloroquine-sensitive NF54 and multidrug-resistant K1 strains of the malarial parasite Plasmodium falciparum. Most of these derivatives showed a 4-49 and 5-17-fold increase in activity
Antiprotozoal activities of epimeric aminobicycles (Publications)
organism of East African sleeping sickness, and Plasmodium falciparum K-1, a multiresistant protozoan parasite which causes Malaria tropica. The results are compared to the activities of their formerly synthesized
Diamidines for human African trypanosomiasis (Publications)
drug must be administered parenterally and is active against first-stage HAT only, prior to the parasites causing neurological deterioration through invasion of the CNS. A major research effort to design
Die Bedeutung der Anamnese bei Erkrankungen nach Tropenaufenthalt (Publications)
the first symptoms is related to the course of tropical diseases, prepatency and survival time of parasites