High prevalence of <em>Strongyloides stercoralis</em> among school children in rural Côte d'Ivoire (Publications)
school ranged between 4.0 and 48%. Because S. stercoralis is a neglected nematode, yet an important parasite from a public health perspective, surveys should consider the use of appropriate diagnostic methods
Studies on <em>Trypanosoma (Nannomonas) congolense</em> IV. Experimental immunization of mice against tsetse fly challenge (Publications)
this same stock. The immunity was stock-specific and directed against the metacyclic forms of the parasite, but was short-lived
Novel diamidines with activity against <em>Babesia divergens</em> <em>in vitro</em> and <em>Babesia microti in vivo</em> (Publications)
diminazene and pentamidine, are well-studied chemotherapeutic agents with significant activity against parasitic diseases. The in vitro activities of novel diamidine compounds against the Babesia divergens strains
High prevalence of <em>Strongyloides stercoralis</em> among school children in rural Côte d'Ivoire (Publications)
school ranged between 4.0 and 48%. Because S. stercoralis is a neglected nematode, yet an important parasite from a public health perspective, surveys should consider the use of appropriate diagnostic methods
Spiroindolones, a potent compound class for the treatment of malaria (Publications)
Spiroindolones rapidly inhibit protein synthesis in P. falciparum, an effect that is ablated in parasites bearing nonsynonymous mutations in the gene encoding the P-type cation-transporter ATPase4 (PfATP4)
Ancistrotanzanine A, the first 5,3'-coupled naphthylisoquinoline alkaloid, and two further, 5,8'-linked related compounds from the newly described... (Publications)
while 5-7 displayed moderately potent antiplasmodial activities against Plasmodium falciparum parasites
Anilinoquinoline based inhibitors of trypanosomatid proliferation (Publications)
leishmaniasis). In addition, sub-micromolar compounds were identified that inhibit proliferation of the parasites that cause African animal trypanosomiasis, T. congolense and T. vivax. We have found that this set
Rhabdopeptide/Xenortide-like peptides from <em>Xenorhabdus innexi </em>with terminal amines showing potent antiprotozoal activity (Publications)
(1D) and two-dimensional (2D) NMR. They were evaluated for their activities against protozoan parasites and cytotoxicity against rat skeletal myoblasts (L6 cells). All tested compounds exhibited strong
Methionine-containing rhabdopeptide/xenortide-like peptides from heterologous expression of the biosynthetic gene cluster <em>kj12ABC</em> in... (Publications)
acids such as valine, leucine, or phenylalanine revealed good activities of 2-7 against protozoan parasites and no cytotoxicity against mammalian L6 cells.
<em>In vitro </em>drug efficacy testing against <em>Trypanosoma brucei</em> (Publications)
human African trypanosomiasis has demonstrated the high predictive value of cell-based assays for parasite chemotherapy. Here we describe three in vitro drug susceptibility tests with Trypanosoma brucei
