Indigenous <em>Plasmodium malariae</em> infection in an endemic population at the Thai-Myanmar border (Publications)
Plasmodium malariae is a neglected malaria parasite. It has wide geographic distribution and, although often associated with mild malaria, is linked to a high burden of anemia and nephrotic syndromes.
Identification of steroid-like natural products as antiplasmodial agents by 2D and 3D similarity-based virtual screening (Publications)
The virtual screening strategy resulted in the identification of nine new compounds that inhibited parasite growth with IC50 values of
Heterogeneities in the transmission of infectious agents: implications for the design of control programs (Publications)
known as the 20/80 rule. The rule applies to a variety of disease systems, including vector-borne parasites and sexually transmitted pathogens. The rule implies that control programs targeted at the "core"
Mining Sudanese medicinal plants for natural compounds against malaria and neglected tropical diseases (Publications)
Tropical parasitic diseases such as malaria, human African trypanosomiasis, Chagas disease, mycetoma, and leishmaniasis affect more than a billion people worldwide and have devastating consequences. There [...] current drugs are problematic given their serious adverse effects and the emergence of drug-resistant parasites. Thus, there is an urgent need for the development of new, efficacious, safe, and cost-effective [...] these compounds, quercetin-3,7-dimethylether and ayanin were the most...
Mining Sudanese medicinal plants for natural compounds against malaria and neglected tropical diseases (Publications)
Tropical parasitic diseases such as malaria, human African trypanosomiasis, Chagas disease, mycetoma, and leishmaniasis affect more than a billion people worldwide and have devastating consequences. There [...] current drugs are problematic given their serious adverse effects and the emergence of drug-resistant parasites. Thus, there is an urgent need for the development of new, efficacious, safe, and cost-effective [...] these compounds, quercetin-3,7-dimethylether and ayanin were the most...
N-oxide alkaloids from <em>Crinum amabile</em> (Amaryllidaceae) (Publications)
structures (augustine N-oxide and buphanisine N-oxide) were structurally elucidated by NMR. Anti-parasitic and cholinesterase (AChE and BuChE) inhibitory activities of six alkaloids isolated from this species
Comparative morphometric analysis of bloodstream and lymph forms of <em>Trypanosoma (T.)</em> <em>brucei brucei</em> grown<em> in vitro</em> and<em>... (Publications)
d. A Coulter Channelyzer was used for the first time to measure the mean cell volume of living parasites. In vitro, the monomorphic trypanosomes between the feeder layer cells showed lower values for
<em>Schistosomiasis mansoni</em> in the hamster: cellular and humoral immune responses to soluble egg antigens (SEA) (Publications)
Schistosoma mansoni infection in the hamster. No immune response to SEA could be detected before the parasite had started oviposition. The liver granuloma size reached a maximum 6 weeks after infection and
Cystic echinococcosis of the liver: a primer for hepatologists (Publications)
and neglected disease with a worldwide distribution. The liver is the most frequent location of parasitic cysts. In humans, its clinical spectrum ranges from asymptomatic infection to severe, potentially
Uses of mosquito-stage transmission-blocking vaccines against <em>Plasmodium falciparum</em> (Publications)
control will be limited. Vaccine combination will also protect against selection of insensitive parasites. Simulations indicate that TBVs will reduce risks of reestablishment of transmission when vector
