Antiprotozoal activity profiling of approved drugs: a starting point toward drug repositioning (Publications)
repositioning potential for neglected diseases was assembled and tested in vitro against four protozoan parasites associated with the aforementioned diseases. Several drugs and drug classes showed in vitro activity
The epidemiology of multiple <em>Plasmodium falcpiarum</em> infections. 11. Premunition in <em>Plasmodium falciparum </em>infection: insights from the... (Publications)
low-level chronic parasitaemia. This appears to confer cross-protection against newly inoculated parasites, via partially genotype-specific responses which are short-term, lasting little longer than the
Uses of mosquito-stage transmission-blocking vaccines against <em>Plasmodium falciparum</em> (Publications)
control will be limited. Vaccine combination will also protect against selection of insensitive parasites. Simulations indicate that TBVs will reduce risks of reestablishment of transmission when vector
<em>Schistosomiasis mansoni</em> in the hamster: cellular and humoral immune responses to soluble egg antigens (SEA) (Publications)
Schistosoma mansoni infection in the hamster. No immune response to SEA could be detected before the parasite had started oviposition. The liver granuloma size reached a maximum 6 weeks after infection and
Alkaloids from <em>Nerine filifolia</em> (Publications)
(L6) cells and exhibited no anti-protozoal activity in an in vitro screen against four different parasitic protozoa
First generation leishmaniasis vaccines: A review of field efficacy trials (Publications)
First generation candidate vaccines against leishmaniasis, prepared using inactivated whole parasites as their main ingredient, were considered as promising because of their relative ease of production
Cystic echinococcosis of the liver: a primer for hepatologists (Publications)
and neglected disease with a worldwide distribution. The liver is the most frequent location of parasitic cysts. In humans, its clinical spectrum ranges from asymptomatic infection to severe, potentially
Comparative morphometric analysis of bloodstream and lymph forms of <em>Trypanosoma (T.)</em> <em>brucei brucei</em> grown<em> in vitro</em> and<em>... (Publications)
d. A Coulter Channelyzer was used for the first time to measure the mean cell volume of living parasites. In vitro, the monomorphic trypanosomes between the feeder layer cells showed lower values for
N-oxide alkaloids from <em>Crinum amabile</em> (Amaryllidaceae) (Publications)
structures (augustine N-oxide and buphanisine N-oxide) were structurally elucidated by NMR. Anti-parasitic and cholinesterase (AChE and BuChE) inhibitory activities of six alkaloids isolated from this species
<em>Plasmodium falciparum pfhrp2</em> and <em>pfhrp3</em> gene deletions among patients enrolled at 100 health facilities throughout Tanzania:... (Publications)
for only pfhrp2 (n = 9) or only pfhrp3 (n = 6). No dual pfhrp2/3 deleted parasites were observed. This survey found that parasites with these gene deletions are rare in Tanzania, and estimated that 0.24%
