A recombinant blood-stage malaria vaccine reduces<em> Plasmodium falciparum</em> density and exerts selective pressure on parasite populations in a... (Publications)
confidence limits: 13%, 84%) reduction in parasite density in children not pretreated with sulfadoxine-pyrimethamine. Vaccinees had a lower prevalence of parasites carrying the MSP2-3D7 allelic form (cor [...] with FC27-type parasites. These results demonstrate functional activity of Combination B against P. falciparum in individuals with previous malaria exposure. The specific effects on parasites with particular [...] least in part, accounted for the activity. The vaccine-induced selection...
Species diversity and acquisition of gastrointestinal parasites in calves aged 0-13 months in periurban livestock production in Mali (Publications)
of birth on parasite numbers and diversity. Parasite number and burden increased with age. In the age class 4-13 months animals carried already up to eight different gastrointestinal parasite species. Parasite [...] Parasite spectrum found included I I nematodes, 3 cestodes and I protozoan parasite. The most frequent parasite species found were Haemonchus placei (age class 0-1 month: 7%, 1-4 months: 38%, 4-13 months: [...] inspections on 51 calves were conducted to investigate acquisition and...
<em>Plasmodium falciparum</em> infections are associated with agglutinating antibodies to parasite-infected erythrocyte surface antigens among healthy... (Publications)
detectable infection. We suggest that parasitization status may be an important consideration in longitudinal assessments of the protective role of some anti-parasite immune responses and support this suggestion
Genetic diversity of <em>Plasmodium falciparum</em> parasites from Kenya is not affected by antifolate drug selection (Publications)
selection for genes that confer drug resistance is not a factor in reducing the genetic diversity of parasite clones in a patient
Isothermal microcalorimetry accurately detects bacteria, tumorous microtissues, and parasitic worms in a label-free well-plate assay (Publications)
cancer research, diagnostics and development of new antitumor drugs. For parasitic worms, the technique allows assessment of the parasite survival using motor and metabolic activities even with a single worm