Alkaloid constituents of the amaryllidaceae plant amaryllis belladonna L (Publications)
and spectrometric methods, including GC-MS and 2D NMR. In vitro screening against four different parasitic protozoa (Trypanosoma cruzi, T. brucei rhodesiense, Leishmania donovani and Plasmodium falciparum)
Multiplicity of asymptomatic <em>Plasmodium falciparum </em>infections and risk of clinical malaria: a systematic review and pooled analysis of... (Publications)
BACKGROUND: The malaria parasite Plasmodium falciparum holds an extensive genetic polymorphism. In this pooled analysis, we investigate how the multiplicity, i.e. the number of co-infecting clones, in
Deworming children for soil-transmitted helminths in low and middle-income countries: systematic review and individual participant data network... (Publications)
Intestinal parasites affect millions of children globally. We aimed to assess effects of deworming children on nutritional and cognitive outcomes across potential effect modifiers using individual participant
Study of drug particle distributions within mini-tablets using synchrotron X-ray microtomography and superpixel image clustering (Publications)
had a weight of 9.5 mg and a drug load from 2.5% to 20%. Moxidectin, a drug used for treatment of parasitic infections, was used as a model compound. Drug content covered a range from 91% to 121% of the target
Antiprotozoal activities of organic extracts from French marine seaweeds (Publications)
(France) coast. We tested them in vitro against the protozoa responsible for three major endemic parasitic diseases: Plasmodium falciparum, Leishmania donovani and Trypanosoma cruzi. The selectivity of the
IgE antibodies are more species-specific than IgG antibodies in human onchocerciasis and lymphatic filariasis (Publications)
antigens showed that in all instances there was significantly less cross-reactivity with heterologous parasite antigens (i.e. higher species specificity) in the IgE antibody response to filarial infection than
Ancistectorine D, a naphthylisoquinoline alkaloid with antiprotozoal and antileukemic activities, and further 5,8'- and 7,1'-linked metabolites from... (Publications)
constituents in African taxa. Ancistectorine D (5) shows promising activities against the protozoan parasites Trypanosoma cruzi and Leishmania donovani, and it was likewise found to display strong cytotoxic
Host-directed therapies for infectious diseases: current status, recent progress, and future prospects (Publications)
progress in identifying host-directed therapies as adjunct treatment options for bacterial, viral, and parasitic infectious diseases.
A sero-epidemiological approach to explore transmission of <em>Mycobacterium ulcerans</em> (Publications)
were included in the study. While first serological responses to the mosquito transmitted malaria parasite Plasmodium falciparum and to soil transmitted Strongyloides helminths emerged around the age of
Immunization of malaria pre-exposed volunteers with PfSPZ Vaccine elicits long-lived IgM invasion-inhibitory and complement-fixing antibodies (Publications)
assessment of PfSPZ Vaccine-induced antibody responses could be more sensitive if they include parasite specific IgM in addition to IgG antibodies.