Searched for parasites.

1. A Tropical Disease in Switzerland: Call for Coordinated Action on Chagas Disease (News)

   A Tropical Disease in Switzerland: Call for Coordinated Action on Chagas Disease

   Relevance:
   https://www.swisstph.ch/en/news/a-tropical-disease-in-switzerland-call-for-coordinated-action-on-chagas-disease

   Chagas disease, caused by the parasite Trypanosoma cruzi , affects about 7 to 8 million people worldwide, mainly in Latin America. The parasite can be transmitted by triatomine bugs, via food, blood t

2. Species composition, infection rate and detection of resistant alleles in <em>Anopheles funestus</em> (Diptera: Culicidae) from Lare, a malaria... (Publications)

   Species composition, infection rate and detection of resistant alleles in <em>Anopheles funestus</em> (Diptera: Culicidae) from Lare, a malaria hotspot district of Ethiopia

   Relevance:

   N485I, kdr L1014F, L1014S, and CYP6P9a TaqMan qPCR was used to detect the infective stage of the parasite from field collected adult female An. funestus populations. METHODS: Adult female mosquito collection [...] dissection, the TaqMan qPCR assay was used to investigate the presence of the infective stage Plasmodium parasite species. RESULTS: A total of 1086 adult female An. funestus mosquitoes were collected during the

3. Molecular Signatures can Predict the Efficacy of Malaria Vaccines (News)

   Molecular Signatures can Predict the Efficacy of Malaria Vaccines

   Relevance:
   https://www.swisstph.ch/en/news/news-detail/news/molecular-signatures-can-predict-the-efficacy-of-malaria-vaccines

   deaths in 2018. The main obstacles for the development of an effective vaccine against such a complex parasite are the lack of immune markers of protection and the poor understanding of the mechanisms underlying [...] the CPS vaccine, based on the inoculation of attenuated sporozoites of the Plasmodium falciparum parasite, which has a high efficacy in adult volunteers against controlled human malaria infection. The

4. BSL-3 Laboratories | Research Infrastructure at Swiss TPH (Page)

   BSL-3 Laboratories | Research Infrastructure at Swiss TPH

   Relevance:
   https://www.swisstph.ch/en/research/research-infrastructure/bsl-3-laboratories

   respirator. Contact Prof Sebastien Gagneux Kreuzstrasse 2 4123 Allschwil Related Units and Groups Parasite Chemotherapy Tuberculosis Ecology and Evolution Tuberculosis Immunology Molecularimmunology Related

5. UCT943, a next generation <em>Plasmodium falciparum</em> PI4K inhibitor preclinical candidate for the treatment of malaria (Publications)

   UCT943, a next generation <em>Plasmodium falciparum</em> PI4K inhibitor preclinical candidate for the treatment of malaria

   Relevance:

   series was optimized to improve properties such as solubility and antiplasmodial potency across the parasite lifecycle, leading to the 2-aminopyrazine UCT943. The compound displayed higher asexual blood stage

6. Embedded-deep-learning-based sample-to-answer device for on-site malaria diagnosis (Publications)

   Embedded-deep-learning-based sample-to-answer device for on-site malaria diagnosis

   Relevance:

   staining patches. Embedded-deep-learning-enabled miLab™ was utilized to detect and classify malarial parasites from autofocused images of stained blood cells using an internal optical system. The results of

7. Sustained malaria control over an 8-year period in Papua New Guinea: the challenge of low-density asymptomatic <em>Plasmodium</em> infections (Publications)

   Sustained malaria control over an 8-year period in Papua New Guinea: the challenge of low-density asymptomatic <em>Plasmodium</em> infections

   Relevance:

   P. vivax prevalence decreased from 42% in 2006 to 13% in 2010 but then increased to 20% in 2014. Parasite densities decreased 5-fold from 2006 to 2010; 72% of P. falciparum and 87% of P. vivax infections

8. Repeated mosquito net distributions, improved treatment, and trends in malaria cases in sentinel health facilities in Papua New Guinea (Publications)

   Repeated mosquito net distributions, improved treatment, and trends in malaria cases in sentinel health facilities in Papua New Guinea

   Relevance:

   significant reduction was associated with ACT introduction. Plasmodium falciparum remained the dominant parasite in all sentinel health facilities. Resurgence occurred in one site in which a shift to early and

9. Informed consent procedure in a double blind randomized anthelminthic trial on Pemba Island, Tanzania: do pamphlet and information session increase... (Publications)

   Informed consent procedure in a double blind randomized anthelminthic trial on Pemba Island, Tanzania: do pamphlet and information session increase caregivers knowledge?

   Relevance:

   caregivers' knowledge for some of the questions. Most of these questions were either related to the parasite (hookworm) or to the trial design (study procedures). CONCLUSIONS: In conclusion, within our trial

10. malERA: an updated research agenda for combination interventions and modelling in malaria elimination and eradication (Publications)

    malERA: an updated research agenda for combination interventions and modelling in malaria elimination and eradication

    Relevance:

    specific interventions after local transmission is interrupted, and evaluate the risk and impact of parasite drug resistance and vector insecticide resistance. However, modelling intervention package deployment