The WHO ultrasonography protocol for assessing hepatic morbidity due to <em>Schistosoma mansoni</em>: acceptance and evolution over 12 years (Publications)
ultrasound" from 2001 to 2012 was performed. Case reports, reviews, reports on abnormalities due to parasites other than S. mansoni, organ involvement other than the human liver, and reports where ultrasound
Aquaglyceroporin-null trypanosomes display glycerol transport defects and respiratory-inhibitor sensitivity (Publications)
pentamidine-uptake, and melarsoprol treatment-failure has been found to be due to AQP2-defects in these parasites. To further probe the roles of these transporters, we assembled a T. b. brucei strain lacking all
A worldwide map of <em>Plasmodium falciparum</em> K13-propeller polymorphisms (Publications)
we observed a broad array of rare nonsynonymous mutations that were not associated with delayed parasite clearance. The gene-edited Dd2 transgenic line with the A578S mutation, which expresses the most
Combined stool-based multiplex PCR and microscopy for enhanced pathogen detection in patients with persistent diarrhoea and asymptomatic controls from... (Publications)
detection tests for the diagnosis of diarrhoeagenic pathogens. Overall, 20 different bacteria, parasites and viruses were detected by the suite of diagnostic methods employed. At least one pathogen was
Effect of artemether administered alone or in combination with praziquantel to mice infected with <em>Plasmodium berghei </em>or <em>Schistosoma... (Publications)
efficacies of artemether in mice infected with Plasmodium berghei or Schistosoma mansoni or both parasites concurrently. Three oral doses of 400mg/kg artemether at 14-day intervals reduced total and female
Microhabitat preferences of <em>Biomphalaria pfeifferi</em> and <em>Lymnaea natalensis</em> in a natural and a man-made habitat in southeastern... (Publications)
Schistosoma mansoni is an important human parasitic disease which is widespread throughout Africa. As Biomphalaria pfeifferi snails act as intermediate host, knowledge of their population ecology is an
Mapping hotspots of malaria transmission from pre-existing hydrology, geology and geomorphology data in the pre-elimination context of Zanzibar,... (Publications)
malaria elimination programmes, especially for tackling outdoor biting species and for eliminating parasite and vector populations when they are most vulnerable during the dry season. Effective larval source
Compounds structurally related to ellagic acid show improved antiplasmodial activity (Publications)
downregulation of most antioxidant genes studied and impaired mainly the trophozoite stage of the parasites. In addition, EA, CEA, and FEA were found to strongly inhibit in vitro heme aggregation. In vitro
Synthesis and biological evaluation of organoruthenium complexes with azole antifungal agents. First crystal structure of a tioconazole metal complex (Publications)
showed statistically significant effects. Mcz and its complexes were also tested against the human parasite Schistosoma mansoni and revealed schistocidal activity at 10-100 mu g/mL in vitro
Efficacy of the cyclooctadepsipeptide PF1022A against <em>Heligmosomoides bakeri in vitro</em> and <em>in vivo</em> (Publications)
the fungus, Mycelia sterilia, is characterized by a broad spectrum of activity against different parasitic gastrointestinal nematodes of livestock. In the present work the anthelmintic activity of PF1022A
