Prevalence of intestinal protozoa infection among school-aged children on Pemba Island, Tanzania, and effect of single-dose albendazole, nitazoxanide... (Publications)
associated with malabsorption syndromes and gastrointestinal morbidity. Since diagnosis of these parasites is difficult, prevalence data on intestinal protozoa is scarce. METHODS: We collected two stool
Pharmacokinetics-pharmacodynamics analysis of spiroindolone analogs and KAE609 in a murine malaria model (Publications)
concentrations remained above 2*IC99 within 48 hrs (%T> TRE) and the AUC0-48/TRE correlated well with parasite reduction (R2=0.97 and 0.95, respectively), less so for the Cmax/TRE (R2=0.88). The present results
Prevalence and factors associated with convulsive status epilepticus in Africans with epilepsy (Publications)
Uganda; and Kilifi, Kenya. We performed serologic assessment for the presence of antibodies to parasitic infections and HIV and determined adherence to antiepileptic drugs. Consequences of CSE were assessed
Macyranones: structure, biosynthesis, and binding mode of an unprecedented epoxyketone that targets the 20S proteasome (Publications)
active beta5 subunit of the proteasome. Macyranone A exhibits a potent inhibitory effect against the parasites Trypanosoma brucei rhodesiense and Leishmania donovani with IC50 values of 1.55 and 0.22 muM, r
The cross-reactive immune response between infective larvae and adult worms of <em>Acanthocheilonema </em>(Dipetalonema) viteae is dominated by... (Publications)
cuticula of either the L3 or adult worms, this response may not contribute to protection against the parasite.
Anémie dans une école du Cambodge rural: détection, prévalence et liens avec les parasitoses intestinales et la malnutrition (Publications)
study was to assess the prevalence of anaemia and two of its possible driving factors, intestinal parasites and general malnutrition; a secondary objective was to assess the accuracy of haemoglobin colour
Towards improved diagnosis of zoonotic trematode infections in Southeast Asia (Publications)
use of this approach. The future development of virtual microscopy to be used for diagnosis of parasitic infections in the field could make ordinary microscopy obsolete by electronically capturing specimens
A stable, oligosymptomatic malaria focus in Thailand (Publications)
of a non-migratory farming village in south-eastern Thailand was visually examined for malaria parasites monthly for 2 years. Nearly 97% of the population had at least one (median = 5) patent Plasmodium
Pharmacokinetics-pharmacodynamics analysis of spiroindolone analogs and KAE609 in a murine malaria model (Publications)
concentrations remained above 2*IC99 within 48 hrs (%T> TRE) and the AUC0-48/TRE correlated well with parasite reduction (R2=0.97 and 0.95, respectively), less so for the Cmax/TRE (R2=0.88). The present results
Population pharmacokinetics of mefloquine, piperaquine and artemether-lumefantrine in Cambodian and Tanzanian malaria patients (Publications)
(variability) could generate low plasma levels that contribute to selecting for drug-resistant parasites
