Repositioning and characterization of 1-(pyridin-4-yl)pyrrolidin-2-one derivatives as <em>Plasmodium </em>cytoplasmic prolyl-trna synthetase... (Publications)
relative high propensity to develop resistance in vitro (minimum inoculum resistance of 8 x 10(5) parasites at a selection pressure of 3 x IC50) constitute unfavorable features for treatment of malaria. However
An individual-based model of <em>Plasmodium falciparum</em> malaria transmission on the coast of Kenya (Publications)
immigration (> 0.3%) by infected people into the community could prevent local extinction of the parasite. In intermediate and high transmission areas, reduction in prevalence is short-lived and the probability
Macyranones: structure, biosynthesis, and binding mode of an unprecedented epoxyketone that targets the 20S proteasome (Publications)
active beta5 subunit of the proteasome. Macyranone A exhibits a potent inhibitory effect against the parasites Trypanosoma brucei rhodesiense and Leishmania donovani with IC50 values of 1.55 and 0.22 muM, r
Acute schistosomiasis: a risk underestimated by travelers and a diagnosis frequently missed by general practioners - a cluster analysis of 42... (Publications)
a returning traveler with fever. If eosinophilia is detected, it should prompt the search for a parasitic disease.
Prevalence and factors associated with convulsive status epilepticus in Africans with epilepsy (Publications)
Uganda; and Kilifi, Kenya. We performed serologic assessment for the presence of antibodies to parasitic infections and HIV and determined adherence to antiepileptic drugs. Consequences of CSE were assessed
<em>Albatrellus confluens</em> (Alb. & Schwein.) Kotl. & Pouz.: natural fungal compounds and synthetic derivatives with <em>in vitro</em>... (Publications)
control measure, but the use of the few available drugs is giving rise to increased resistance of the parasites to the drugs. Different approaches are needed to come up with new therapeutic agents against these
Strong off-target antibody reactivity to malarial antigens induced by RTS,S/AS01E vaccination is associated with protection (Publications)
The RTS,S/AS01E vaccine targets the circumsporozoite protein (CSP) of the Plasmodium falciparum parasite. Using protein microarrays, levels of IgG to 1,000 P. falciparum antigens were measured in 2,138
Anémie dans une école du Cambodge rural: détection, prévalence et liens avec les parasitoses intestinales et la malnutrition (Publications)
study was to assess the prevalence of anaemia and two of its possible driving factors, intestinal parasites and general malnutrition; a secondary objective was to assess the accuracy of haemoglobin colour
Antiprotozoal isoflavan quinones from <em>Abrus precatorius</em> ssp. <em>africanus</em> (Publications)
extracts from selected South African plants was screened in vitro against a panel of protozoan parasites, Plasmodium falciparum, Trypanosoma brucei rhodesiense, and Leishmania donovani. A CH2Cl2/MeOH (1
Towards improved diagnosis of zoonotic trematode infections in Southeast Asia (Publications)
use of this approach. The future development of virtual microscopy to be used for diagnosis of parasitic infections in the field could make ordinary microscopy obsolete by electronically capturing specimens
