The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases - part I (Publications)
Infections with protozoan parasites are a major cause of disease and mortality in many tropical countries of the world. Diseases caused by species of the genera Trypanosoma (Human African Trypanosomiasis
Health workers' use of malaria rapid diagnostic tests (RDTs) to guide clinical decision making in rural dispensaries, Tanzania (Publications)
(RDTs) were developed as an alternative to microscopy for malaria diagnosis. The RDTs detect malaria parasite antigen(s) in whole blood with high sensitivity and specificity. We assessed health worker malaria
Effect of schistosomiasis and soil-transmitted helminth infections on physical fitness of school children in Côte d'Ivoire (Publications)
7, 53.1, 52.2, 52.6 and 55.6 ml kg(-1) min(-1), respectively. The VO(2) max of children with no parasite infections was 53.5 ml kg(-1) min(-1). No statistically significant difference was detected between
Spatial risk profiling of <em>Plasmodium falciparum</em> parasitaemia in a high endemicity area in Côte d'Ivoire (Publications)
ren were infected with P. falciparum and the mean parasitaemia among infected children was 959 parasites/mul of blood. Age, socioeconomic status, not sleeping under a bed net, coverage rate with bed nets
Compensatory density feedback of <em>Oncomelania hupensis</em> populations in two different environmental settings in China (Publications)
Our findings indicate that integrated schistosomiasis control measures must continue to reduce parasite abundance further because intermediate host snail populations tend to grow exponentially at low
A new double-antibody sandwich ELISA targeting <em>Plasmodium falciparum</em> aldolase to evaluate anti-malarial drug sensitivity (Publications)
twenty possibilities, the most sensitive antibody pair was selected and used to quantitatively detect parasite aldolase in infected blood lysates. RESULTS: A total of 34 compounds with anti-malarial activity
Helminthiases in the People's Republic of China: status and prospects (Publications)
estimates; (ii) diagnostics and antigen characterisation; (iii) drug and vaccine development; (iv) host-parasite interactions and snail genetics; (v) surveillance and public health response; and (vi) capacity
Accuracy of different diagnostic techniques for <em>Schistosoma haematobium</em> to estimate treatment needs in Zimbabwe: application of a... (Publications)
needs for Schistosoma haematobium are commonly evaluated using urine filtration with detection of parasite eggs under a microscope. A common symptom of S. haematobium is hematuria, the passing of blood in
Routine delivery of artemisinin-based combination treatment at fixed health facilities reduces malaria prevalence in Tanzania: an observational study (Publications)
to reduce malaria transmission due to their ability to kill both asexual blood stages of malaria parasites, which sustain infections over long periods and the immature derived sexual stages responsible for
A novel approach for measuring the burden of uncomplicated <em>Plasmodium falciparum</em> malaria: application to data from Zambia (Publications)
clinical cases or episodes, with the main data sources being reports from health facilities and parasite prevalence surveys. The use of burden estimates that do not consider effects of treatment, leads
