Modeling the persistence of <em>Opisthorchis viverrini</em> worm burden after mass-drug administration and education campaigns with systematic... (Publications)
Opisthorchis viverrini is a parasitic liver fluke contracted by consumption of raw fish, which affects over 10 million people in Southeast Asia despite sustained control efforts. Chronic infections are
Human African trypanosomiasis (Publications)
Human African trypanosomiasis (HAT) is a parasitic disease caused by Trypanosoma brucei gambiense or T.b. rhodesiense, transmitted by tsetse flies (Glossina spp.). HAT has a prominent history as it received
<em>Trichuris muris</em> egg-hatching assay for anthelminthic drug discovery and characterization (Publications)
stage of Trichuris spp. We examined bacterial species dependent egg hatching of the murine model parasite Trichuris muris and identified Escherichia coli, Pseudomonas aeruginosa and Enterobacter hormaechei
HPLC-based activity profiling for antiplasmodial compounds in the traditional Indonesian medicinal plant <em>Carica papaya</em> L (Publications)
data, and by X-ray crystallography. Compounds were tested for bioactivity in vitro against four parasites (Trypanosoma brucei rhodesiense, Trypanosoma cruzi, Leishmania donovani, and Plasmodium falciparum)
<em>Trypanosoma brucei</em> aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic... (Publications)
brucei aquaglyceroporin 2 (TbAQP2) caused melarsoprol/pentamidine cross-resistance (MPXR) in these parasites and the current study aims to delineate the mechanism by which this occurs. METHODS: The TbAQP2
Effects of inflammation and <em>Plasmodium falciparum</em> infection on soluble transferrin receptor and plasma ferritin concentration in different... (Publications)
BACKGROUND: Iron deficiency (ID) is a major cause of anemia, along with other nutritional, parasitic, and genetic factors. Accurate biomarkers are needed to estimate the relative contribution of ID to
Surveillance and response systems for elimination of tropical diseases: summary of a thematic series in Infectious Diseases of Poverty (Publications)
s pertaining to surveillance-response mechanisms were both hosted by the National Institute of Parasitic Diseases (NIPD) in Shanghai, coupled with P.R. China's growing importance with regard to the control
<em>Ent</em>-pimarane and <em>ent</em>-kaurane diterpenes from <em>Aldama discolor</em> (Asteraceae) and their antiprotozoal activity (Publications)
identified as major compound in the A. discolor extract and explains its high activity against this parasite (100% growth inhibition at 2 mu g/mL).
Microscopic diagnosis of sodium acetate-acetic acid-formalin-fixed stool samples for helminths and intestinal protozoa: a comparison among European... (Publications)
network of reference laboratories is necessary to further enhance both accuracy and uniformity in parasite diagnosis
Tribendimidine: a promising, safe and broad-spectrum anthelmintic agent from China (Publications)
a broad spectrum of activity. Tribendimidine was first synthesized at the National Institute of Parasitic Diseases in Shanghai in the mid 1980s. In laboratory studies, tribendimidine showed high efficacy
