Synthesis and antimalarial and antituberculosis activities of a series of natural and unnatural 4-methoxy-6-styryl-pyran-2-ones, dihydro analogues and... (Publications)
head-to-tail photodimers 5 and 34 exhibited moderate IC(50)s of 2.3 to 17muM towards several of the parasitic organisms, while the aniba-dimer-type asymmetric dimers 31 and 33 were identified as being moderately
Tribendimidine: a promising, safe and broad-spectrum anthelmintic agent from China (Publications)
a broad spectrum of activity. Tribendimidine was first synthesized at the National Institute of Parasitic Diseases in Shanghai in the mid 1980s. In laboratory studies, tribendimidine showed high efficacy
Immunoglobulin G subclass-specific responses against <em>Plasmodium falciparum</em> merozoite antigens are associated with control of parasitemia and... (Publications)
infections. However, no antibody response was significantly associated with protection from parasitization per se. Our findings have major implications for understanding human immunity and for malaria
Anti-protozoal activities of cembrane-type diterpenes from Vietnamese soft corals (Publications)
(Pf). Twelve of the tested compounds displayed significant activity against at least one of the parasites. Specifically, 7S,8S-epoxy-1,3,11-cembratriene-16-oic methyl ester (1), (1R,4R,2E,7E,11E)-cembra-2
Malaria case management by community health workers in the Central African Republic from 2009-2014: overcoming challenges of access and instability... (Publications)
200,000 people who consulted a CHW during this period, 81% were found to be positive for malaria parasites by RDT. In total, 98.9% of these positive cases were appropriately treated with artemisinin-based
Evaluation of the pharmacokinetic-pharmacodynamic relationship of praziquantel in the <em>Schistosoma mansoni</em> mouse model (Publications)
remains the drug of choice for the treatment of intestinal and urogenital schistosomiasis. Its anti-parasitic activity resides primarily in the (R)-enantiomer. Hitherto neither the molecular target nor the
Asymptomatic <em>Plasmodium</em> infection and glycemic control in adults: results from a population-based survey in south-central Côte d'Ivoire (Publications)
with HbA1c were obliterated on accounting for FG. We also observed consistent associations with parasite density. CONCLUSIONS: FG-based diabetes diagnosis in the presence of asymptomatic PI may misclassify
<em>Wolbachia</em> bacteria in <em>Mansonella perstans</em> isolates from patients infected in different geographical areas: a pilot study from the... (Publications)
BACKGROUND: Mansonella perstans is a vector-borne filarial parasite widely endemic in sub-Saharan Africa, with sporadic cases in Latin America. Infection is often overlooked; treatment is not standardized
Multiplicity of <em>Plasmodium falciparum</em> infection following intermittent preventive treatment in infants (Publications)
polyclonal infections (69.6% vs. 69.7%; P = 0.99). Adjusting for study site, current and prior malaria, parasite density, and season did not change this finding. CONCLUSIONS: IPTi-SP appears to have no impact
Microscopic diagnosis of sodium acetate-acetic acid-formalin-fixed stool samples for helminths and intestinal protozoa: a comparison among European... (Publications)
network of reference laboratories is necessary to further enhance both accuracy and uniformity in parasite diagnosis
