Chemotherapy of second stage human African trypanosomiasis: comparison between the parenteral diamidine DB829 and its oral prodrug DB868 in vervet... (Publications)
[CNS]) of infection. In response to this largely unmet need for new treatments, the Consortium for Parasitic Drug Development developed novel parenteral diamidines and corresponding oral prodrugs that have
Safety, pharmacokinetic, and efficacy studies of oral DB868 in a first stage vervet monkey model of human African trypanosomiasis (Publications)
healthcare costs of HAT. The development of oral medications is a key objective of the Consortium for Parasitic Drug Development (CPDD). In this study, we investigated the safety, pharmacokinetics, and efficacy
<em>Plasmodium falciparum </em>infection and clinical indicators in relation to net coverage in central Côte d'Ivoire (Publications)
not differ between net-sleepers and non-net-sleepers. Fewer children had parasitaemia > /=1,000 parasites/mul of blood in Bozi in the third compared to the first survey. Fever was poorly correlated with
Naturally acquired immune responses to <em>P. vivax</em> merozoite surface protein 3alpha and merozoite surface protein 9 are associated with reduced... (Publications)
BACKGROUND: Plasmodium vivax is the most geographically widespread human malaria parasite. Cohort studies in Papua New Guinea have identified a rapid onset of immunity against vivax-malaria in children
Effects of hygiene and defecation behavior on helminths and intestinal protozoa infections in Taabo, Côte d'Ivoire (Publications)
Logistic regression models were employed to assess for associations between questionnaire data and parasitic infections. PRINCIPAL FINDINGS: A total of 1,894 participants had complete data records. Parasitological
Malaria infection prevalence and sensitivity of reactive case detection in Zanzibar (Publications)
prevalence of low-density infections results in an RCD system missing a large proportion of the parasite reservoir.
The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases - part II (Publications)
Infections with protozoan parasites are a major cause of disease and mortality in many tropical countries of the world. Diseases caused by species of the genera Trypanosoma (Human African Trypanosomiasis
Self-rated quality of life and school performance in relation to helminth infections: case study from Yunnan, People's Republic of China (Publications)
is needed to further develop these instruments and to validate them in connection with chronic parasitic diseases
Absence of dry season <em>Plasmodium</em> parasitaemia, but high rates of reported acute respiratory infection and diarrhoea in presschool-aged... (Publications)
April 2011 (dry season), assessing three major disease patterns, including malaria. Plasmodium spp. parasite rates were tested among children aged 6--59 months who were recruited from a random selection of
Evaluating different storage media for identification of <em>Taenia saginata</em> proglottids using MALDI-TOF mass spectrometry (Publications)
species-specific helminth diagnosis. However, standardized protocols and commercial databases for parasite identification are currently unavailable, and pre-analytical factors have not yet been assessed
