Identification of oleamide in <em>Guatteria</em> recurvisepala by LC/MS-Based <em>Plasmodium falciparum</em> thioredoxin reductase ligand binding... (Publications)
structure elucidation. PFTrxR is involved in the antioxidant defense and redox regulation of the parasite and is validated as a promising target for therapeutic intervention against malaria. In the present
Impact of artemisinin-based combination therapy and insecticide-treated nets on malaria burden in Zanzibar (Publications)
years. Additional distribution of LLINs in early 2006 resulted in a 10-fold reduction of malaria parasite prevalence. The results indicate that the Millennium Development Goals of reducing mortality in
Community knowledge, attitude, practices and beliefs associated with persistence of malaria transmission in north-western and southern regions of... (Publications)
caused by bathing and drinking un-boiled water, or consuming contaminated food that has malaria parasites without warming it. Reported barriers to malaria prevention and control (by FGD and IDI participants)
The epidemiology of <em>Plasmodium falciparum </em>and <em>Plasmodium vivax</em> in East Sepik Province, Papua New Guinea, pre- and... (Publications)
distribution of free long-lasting insecticidal nets (LLINs), as well as improvements in access to parasite-confirmed diagnosis and effective artemisinin-combination therapy in 2011-2012. METHODS: To study
Pre-existing partner-drug resistance to artemisinin combination therapies facilitates the emergence and spread of artemisinin resistance: a consensus... (Publications)
time step that updates individuals' infection status, treatment status, immunity, genotype-specific parasite densities, and clinical state. We modelled varying access to antimalarial drugs if febrile (coverage
Disparities of <em>Plasmodium falciparum</em> infection, malaria-related morbidity and access to malaria prevention and treatment among school-aged... (Publications)
microscopy and RDT results with a geometric mean of parasitaemia among infected children of 499 parasites/mul of blood. Infection with P. falciparum was significantly associated with sex, socioeconomic
Potential causes and consequences of behavioural resilience and resistance in malaria vector populations: a mathematical modelling analysis (Publications)
malaria. However, it remains unclear which behaviours are most important for buffering mosquito and parasite populations against vector control. METHODS: Simulated life histories were used to compare the impact
What should vaccine developers ask? Simulation of the effectiveness of malaria vaccines (Publications)
is unlikely that any of them will provide long-lasting sterilizing immunity against the malaria parasite. There is great uncertainty about what the minimal vaccine profile should be before registration
Malaria: a major health problem within an oil palm plantation around Popondetta, Papua New Guinea (Publications)
carried out a cross-sectional study within six company villages, which included the determination of parasite rates by conventional microscopy, interviews and haemoglobin measurements. Passive surveillance
Study and implementation of urogenital schistosomiasis elimination in Zanzibar (Unguja and Pemba islands) using an integrated multidisciplinary... (Publications)
ABSTRACT: BACKGROUND: Schistosomiasis is a parasitic infection that continues to be a major public health problem in many developing countries being responsible for an estimated burden of at least 1.4