False-negative malaria rapid diagnostic tests in Rwanda: impact of <em>Plasmodium falciparum</em> isolates lacking <em>hrp2</em> and declining malaria... (Publications)
whether persons with fever should be treated with anti-malarials. However, Plasmodium falciparum parasites with a deletion of the hrp2 gene yield false-negative RDTs and there are concerns the sensitivity
EUR 2.47 Million Grant Awarded to Swiss TPH for Helminth Research (News)
https://www.swisstph.ch/en/news/news-detail/news/eur-247-million-grant-awarded-to-swiss-tph-for-helminth-research
2b studies will assess whether emodepside is superior to albendazole, another treatment against parasitic worm infections. “I speculate that emodepside will emerge as a novel key player in the anthelminthic
Trends of <em>Plasmodium falciparum</em> molecular markers associated with resistance to artemisinins and reduced susceptibility to lumefantrine in... (Publications)
electron transfer polymerase chain reaction (PET-PCR) was used to confirm presence of malaria parasites before capillary sequencing, which targeted two genes: Plasmodium falciparum kelch 13 propeller
Nutritional and health status of children 15 months after integrated school garden, nutrition, and water, sanitation and hygiene interventions: a... (Publications)
health components (SG+) increased children's fruit and vegetable consumption, decreased intestinal parasitic infections and improved hygiene behaviours. TRIAL REGISTRATION: ISRCTN17968589 (date assigned: 17
Assessment of ultra-sensitive malaria diagnosis versus standard molecular diagnostics for malaria elimination: an in-depth molecular community... (Publications)
infections undetectable by standard qPCR increased. INTERPRETATION: Almost all potentially transmitting parasite carriers were identified with us-qPCR on fingerprick blood volumes. Analysing larger blood volumes
Wayanin and guaijaverin, two active metabolites found in a <em>Psidium acutangulum</em> Mart. ex DC (syn. P. persoonii McVaugh) (Myrtaceae)... (Publications)
n of the ethyl acetate soluble fraction (IC50 ranging from 3.4 to < 1microg/mL depending on the parasite strain) led to the isolation of six pure compounds: catechin and five glycosylated quercetin derivatives
Comparison of molecular quantification of <em>Plasmodium falciparum</em> gametocytes by <em>Pfs</em>25 qRT-PCR and QT-NASBA in relation to mosquito... (Publications)
was performed using culture-derived mature Plasmodium falciparum gametocytes from three different parasite isolates (NF54, NF135, NF166). Pfs25 mRNA levels were also determined in samples from clinical trials
Advances with the Chinese anthelminthic drug tribendimidine in clinical trials and laboratory investigations (Publications)
nicotinic acetylcholine receptor agonist. Additional experimental studies revealed that the anti-parasite spectrum of tribendimidine is very broad. Indeed, to date, activity has been documented against
Comparison of community-wide, integrated mass drug administration strategies for schistosomiasis and soil-transmitted helminthiasis: a... (Publications)
soil-transmitted helminthiasis. WHO's recommendations for mass drug administration (MDA) against these parasitic infections emphasise treatment of school-aged children, using separate treatment guidelines for
Performance of a real-time PCR approach for diagnosing <em>Schistosoma haematobium</em> infections of different intensity in urine samples from... (Publications)
BACKGROUND: Efforts to control and eliminate schistosomiasis have accelerated over the past decade. As parasite burden, associated morbidity and egg excretion decrease, diagnosis with standard parasitological
