The non-inferiority of piperonyl-butoxide Yorkool® G3 insecticide-treated nets compared to Olyset®Plus measured by <em>Anopheles arabiensis</em>... (Publications)
efficacy to that of existing standard of care. As part of the WHO Global Malaria Programme (GMP) process of assessment of malaria vector control products, a second-in-class insecticide-treated net (ITN)
Largest Clinical Trial in Africa to Treat COVID-19 Cases is Launched in 13 Countries (News)
https://www.swisstph.ch/en/news/news-detail/news/largest-clinical-trial-in-africa-to-treat-covid-19-cases-is-launched-in-13-countries
begin testing, against a control arm, the HIV antiretroviral combination lopinavir/ritonavir and the malaria drug hydroxychloroquine, which remains the standard of care for COVID-19 today in numerous African [...] the potential therapeutic options being explored by ANTICOV are medicines currently used to treat malaria, HIV, hepatitis C, parasitic infections, and certain cancers. About the consortium Major funding
Expression of the MSPDBL2 antigen in a discrete subset of <em>Plasmodium falciparum</em> schizonts is regulated by GDV1 but may not be linked to... (Publications)
requires further investigation in natural infections where it is under immune selection. IMPORTANCE: Malaria parasites in the blood are remarkably variable, able to switch antigenic targets so they may survive [...] developed specific immune responses. This is one of the challenges in developing vaccines against malaria. MSPDBL2 is a target of naturally acquired immunity expressed in minority proportions of schizonts
Biostatistics | Research at Swiss TPH (Page)
https://www.swisstph.ch/en/about/eph/biostatistics
fields of epidemiology, parasitology and infection biology. Primary areas of applications involve malaria, anaemia, neglected diseases, HIV, mortality, cancer and environmental epidemiology. Research is [...] and stakeholders' analysis Estimating the extent, patterns and consequences of heterogeneity in malaria dynamics EBF - Exclusive breastfeeding: global rates, optimal duration, and a multi-country intervention [...] envres.2024.119224 Related Topics Environment and Health Health...
10 Years Swiss TPH: Integration of the ISPM into the Former Swiss Tropical Institute (News)
https://www.swisstph.ch/en/news/news-detail/news/10-years-swiss-tph-integration-of-the-ispm-into-the-former-swiss-tropical-institute
one roof. STI was especially strong in the areas of research in poverty-related diseases, such as malaria and sleeping sickness, as well as healthcare system research in African countries. ISPM was known [...] this important? Nino Künzli: “There is still a risk of traditional infectious diseases, such as malaria, tuberculosis and HIV/AIDS, but thanks to successful research, these infectious diseases can be treated [...] unhealthy combination. In addition, there has been little research, for...
Media Releases (Page)
https://www.swisstph.ch/en/about/dir/communications/media-releases
01.04.2022 New Swiss TPH Headquarters Opened in Allschwil 03.02.2022 Analysis of 20 Years Finds Malaria Control in Young Children Saves Lives into Adulthood 02.02.2022 The Swiss TPH Travel Clinic Temporarily
Status of insecticide resistance in Papua New Guinea: an update from nation-wide monitoring of anopheles mosquitoes (Publications)
distribution of insecticide-treated nets. Here, we provide an update on phenotypic IR in four highly malaria-endemic areas of PNG. IR against deltamethrin, lambda-cyhalothrin, and dichlorodiphenyltrichloroethane
Additional blood meals increase sporozoite infection in <em>Anopheles</em> mosquitoes but not <em>Plasmodium falciparum</em> genetic diversity (Publications)
multiple blood meals on the number of P. falciparum genotypes developing from polyclonal natural human malaria infections (field-isolates) remains unexplored. Here, we experimentally infect An. gambiae with P
The adjuvant GLA-SE promotes human Tfh cell expansion and emergence of public TCRβ clonotypes (Publications)
vaccine formulations, circulating Tfh cells were expanded in Tanzanian volunteers when an experimental malaria vaccine was adjuvanted in GLA-SE but not when formulated in Alum. The GLA-SE-formulated peptide was
Decreased in vitro susceptibility of <em>Plasmodium falciparum</em> isolates to artesunate, mefloquine, chloroquine, and quinine in Cambodia from 2001... (Publications)
from patients enrolled in therapeutic efficacy studies (TES) conducted by the Cambodian National Malaria Control Program for the routine efficacy monitoring of artemisinin-based combination therapy (ACT)
