An immigration-death model to estimate the duration of malaria infection when detectability of the parasite is imperfect (Publications)
studies of panels of heavily parasitized human hosts where parasites have been typed at regular intervals by PCR. Immigration refers to the acquisition of a new parasitic genotype, occurring at rate lambda [...] refers to the clearance of a parasitic genotype (with rate mu). The models assume that corresponding to each observed process which is the detection or failure to detect a parasitic genotype, is an underlying [...] represent the habitat of the parasites, and (ii) a model that allows for...
Disparities in parasitic infections, perceived ill health and access to health care among poorer and less poor schoolchildren of rural Côte... (Publications)
schoolchildren's parasitic infection status, perceived ill health and access to health care in a large rural part of Cote d'Ivoire. These findings call for more equity-balanced parasitic disease control [...] only few studies analysed inequities within poor rural communities. We investigated disparities in parasitic infections, perceived ill health and access to formal health services among more than 4000 scho
Integrated cytokine and metabolic analysis of pathological responses to parasite exposure in rodents (Publications)
Parasitic infections cause a myriad of responses in their mammalian hosts, on immune as well as on metabolic level. A multiplex panel of cytokines and metabolites derived from four parasite-rodent models [...] characterize the urine and plasma metabolite profiles in infected and noninfected animals. Each parasite generated a unique metabolic signature in the host. Plasma cytokine concentrations were obtained [...] signature which is associated with inflammation and to determine specific...
