Molecular surveillance of drug resistance through imported isolates of <em>Plasmodium falciparum</em> in Europe (Publications)
prevalence of resistance-associated point mutations at relevant codons. In particular, we tested for parasites which were developing resistance to antifolates and chloroquine. The screening results were used
Spirombandakamine A3 and cyclombandakamines A8 and A9, polycyclic naphthylisoquinoline dimers, with antiprotozoal activity, from a Congolese... (Publications)
protozoal pathogen causing malaria, and moderate effects on Trypanosoma brucei rhodesiense, the parasite responsible for African sleeping sickness.
Human African trypanosomiasis in endemic populations and travellers (Publications)
Human African trypanosomiasis (HAT) or sleeping sickness is caused by the protozoan parasites Trypanosoma brucei (T.b.) gambiense (West African form) and T.b. rhodesiense (East African form) that are
Monica Golumbeanu (People)
https://www.swisstph.ch/en/staff/profile/people/monica-golumbeanu
mathematical models of malaria infection dynamics to assess the impact of interventions on host and parasite populations. Previously, Monica obtained a PhD in Computational Biology from ETH Zürich, where she
Barbara Matthys (People)
https://www.swisstph.ch/en/staff/profile/people/barbara-matthys
studies and surveys mainly using quantitative methods in the areas of malaria, human intestinal parasites, iodine and nutritional status, diabetes, quality of health care and health literacy in school-
The drugs we have and the drugs we need against major helminth infections (Publications)
Parasitic worms (helminths) have accompanied humans for thousands of years and, still today, they are pervasive where poverty persists, including large parts of Southeast Asia and the Western Pacific Region
Synthesis, biological evaluation and structure-activity relationships of N-benzoyl-2-hydroxybenzamides as agents active against <em>P. falciparum</em>... (Publications)
series of N-benzoyl-2-hydroxybenzamides was re-purposed for testing against four other protozoan parasites: T. b. rhodesiense, T. cruzi, L. donovani, and P. falciparum (K1 isolate). Structure-activity analyses
Rare human infection with the trematode <em>Echinochasmus japonicus</em> in Lao PDR (Publications)
n of the second intermediate hosts (e.g. freshwater fish) that harbour the metacercariae of the parasite. Here, we report the first three cases of Echinochasmus japonicus infection in Lao PDR. Adult E
Systems parasitology: effects of <em>Fasciola hepatica</em> on the neurochemical profile in the rat brain (Publications)
modulation of immune reactions to minimize inflammatory damage, which may favor the co-existence of the parasite in the host. Subsequent analysis of brain extracts from other trematode infection models (i.e.
Synthesis, solution structure and immune recognition of an epidermal growth factor-like domain from <em>Plasmodium falciparum</em> merozoite surface... (Publications)
immunofluorescence assays to cross-react with native MSP-1 on the surfaces of P. falciparum blood stage parasites. This opens the way for a medicinal chemistry-oriented approach to the study and optimization of
