Characterizing the pharmacological interaction of the antimalarial combination artefenomel-piperaquine in healthy volunteers with induced blood-stage... (Publications)
BACKGROUND: The combination antimalarial artefenomel-piperaquine failed to achieve target efficacy in a phase 2b study in Africa and Vietnam. We retrospectively evaluated whether characterizing the ph
Natural variation in timing of egg hatching, response to water agitation, and bidirectional selection of early and late hatching strains of the... (Publications)
variation in egg hatching and its environmental and genetic determinants in sibling species of the malaria vector Anopheles gambiae s.l. is important for understanding their adaptation to variable aquatic
Scalable camera traps for measuring the attractiveness of sugar baits for controlling malaria and dengue vectors (Publications)
BACKGROUND: Attractive targeted sugar baits (ATSBs) are promising new interventions that can complement existing vector control tools. However, reproducible and quantitative information on the level o
Impact of climate variability and interventions on malaria incidence and forecasting in Burkina Faso (Publications)
BACKGROUND: Malaria remains a climate-driven public health issue in Burkina Faso, yet the interactions between climatic factors and malaria interventions across different zones are not well understood [...] suitability and malaria incidence. Wavelet analysis was conducted to understand better how fluctuations in climatic factors across different time scales and climatic zones affect malaria transmission dynamics [...] . This study estimates time delays in the effects of climatic factors on malar...
Only One Third of Children Receive Appropriate Malaria Care (News)
https://www.swisstph.ch/en/news/news-detail/news/only-one-third-of-children-receive-appropriate-malaria-care
in nine sub-Saharan countries. Major gaps in malaria care in children According to the clinical guidelines, all children with malaria should receive a malaria blood test as well as an appropriate antimalarial [...] (WHO) has called for a renewed focus on malaria ( World Malaria Report 2019 ), including improved and better-enforced guidelines for the clinical management of the disease. To gain more insights regarding [...] at a health facility for treatment. Although 80% of children diagnosed...
Improved Bed Nets for Malaria Control in Tanzania (News)
https://www.swisstph.ch/en/news/news-detail/news/improved-bed-nets-for-malaria-control-in-tanzania
more sustainable malaria interventions, both physically and economically. "More than 2 billion ITNs have been procured for public health. They are an incredibly important aspect of malaria control that have [...] Insecticide-treated bed nets (ITNs) are the most widely adopted preventive measure against malaria. ITNs work by both preventing bites and killing mosquitoes that are searching for humans at night. ITNs [...] ITNs, and in particular long-lasting insecticidal nets (LLINs), represent a...
Mathematical Modelling to Inform Next-Generation Malaria Interventions (News)
https://www.swisstph.ch/en/news/news-detail/news/mathematical-modelling-to-inform-next-generation-malaria-interventions
With increasing threats of malaria drug and insecticide resistance, there is now a need for novel malaria interventions to improve public health. According to the study published in Communications Medicine [...] inform decision-making around malaria interventions, integrating modelling evidence is equally as important. “Modeling evidence can guide and accelerate development of new malaria vaccines, monoclonal antibodies [...] medical interventions for malaria prevention, guided by reference...
R. Geigy Award 2022 Goes to Three Researchers for Work on Malaria and Tuberculosis Control in Africa (News)
https://www.swisstph.ch/en/news/news-detail/news/r-geigy-award-2022-goes-to-three-researchers-for-work-on-malaria-and-tuberculosis-control-in-africa
including cell cultures of malaria parasites, which allows them to test the effect of new vaccines or drugs on malaria transmission. "If we stick to the goal of eliminating malaria, we also need new interventions [...] research platform opens up new perspectives in the fight against malaria In recent decades, there has been great progress in the fight against malaria in Africa. However, many people in endemic areas are still [...] their achievements in the field of setting up a research...
Multi-Insecticide Resistant Malaria Vectors Remain Susceptible to Malathion Insecticide (News)
https://www.swisstph.ch/en/news/news-detail/news/multi-insecticide-resistant-malaria-vectors-remain-susceptible-to-malathion-insecticide
Despite ongoing efforts in malaria control, the progress of malaria prevention has remained stagnant over the past seven years. The World Health Organization estimates a rise in malaria cases from 227 million [...] role in recent years, progress in malaria control was already stalling; with one reason being the increase in insecticide resistance. The main tools in fighting malaria and other vector-borne diseases are [...] indoor residual spraying. The extensive use of insecticides in vector...
Time to Deliver Zero Malaria: Invest, Innovate, Implement (News)
https://www.swisstph.ch/en/news/news-detail/news/time-to-deliver-zero-malaria-invest-innovate-implement
cases of malaria worldwide and 600,000 deaths. Most tragically, most of these deaths were children under the age of five. This year’s World Malaria Day, under the motto “Time to Deliver Zero Malaria: Investment [...] development and the importance of improving health systems. World Malaria Day 2023 at Swiss TPH Swiss TPH actively contributes to global malaria control and elimination by developing new drugs and interventions [...] President of the Swiss Malaria Group. Lengeler emphasised that,...
