Group | Genetic Epidemiology of Non-Communicable Diseases

The group has established one of the largest chronic disease-related biobanks in Switzerland (The SAPALDIA Biobank). The biobank allows for studies on the genetic background of complex chronic diseases and related subclincial phenotypes, with a special focus on phenotypes related to respiratory and cardiovascular health (i.e. lung function, asthma, COPD, heart rate variability, intima-media thickness and renal function).

In the context of international collaborations and genetics consortia, staff members contribute to and lead large meta-analyses to identify novel disease genes and to understand how they modify susceptibility to lifestyle and environmental factors. Studies on the interaction of inherited genetic and epigenetic susceptibility factors with environmental factors, such as air pollution and noise, are a major focus of the group.

Nicole Probst-Hensch

Nicole Probst-Hensch, Professor, PhD (Pharmacy and Epidemiology), MPH

Adebayo-Ojo T.C, Wichmann J, Arowosegbe O.O, Probst-Hensch N, Schindler C, Künzli N. Short-term joint effects of PM10, NO2 and SO2 on cardio-respiratory disease hospital admissions in Cape Town, South Africa. Int J Environ Res Public Health. 2022;19:495. DOI: 10.3390/ijerph19010495

Darkhawaja R.A.M et al. Exploring the role of social capital, self-efficacy and social contagion in shaping lifestyle and mental health among students representing the future healthcare workforce in Palestine: social cohort study protocol. BMJ Open. 2022;12:e049033. DOI: 10.1136/bmjopen-2021-049033

Allabadi H et al. Posttraumatic stress disorder predicts poor health-related quality of life in cardiac patients in Palestine. PLoS One. 2021;16(7):e0255077. DOI: 10.1371/journal.pone.0255077

Beloconi A, Probst-Hensch N, Vounatsou P. Spatio-temporal modelling of changes in air pollution exposure associated to the COVID-19 lockdown measures across Europe. Sci Total Environ. 2021;787:147607. DOI: 10.1016/j.scitotenv.2021.147607

Bringolf-Isler B et al. COVID-19 pandemic and health related quality of life in primary school children in Switzerland: a repeated cross-sectional study. Swiss Med Wkly. 2021;151:w30071. DOI: 10.4414/SMW.2021.w30071