Unit | Health Interventions

The Health Interventions Unit deals with the development and field testing of new health interventions, with a strong focus on malaria. We operate a dual portfolio of service projects and research studies in a number of countries in Africa South of the Sahara (chiefly Tanzania, Ivory Coast and Democratic Republic of Congo) and in Papua New Guinea. Because of the very applied nature of our work, we collaborate extensively with the service departments in the institute. We also interact regularly with the Health Systems Research and Dynamical Modelling Unit, as well as with the Medical Parasitology and Infection Biology (MPI) research groups.

Research

Research work deals with the integration of new interventions into the health system (for example injectable or rectal artesunate for the treatment of severe malaria), doing trials of new vaccine candidates, developing new treatment algorithms for children with fever, improving the monitoring and evaluation of national programmes, and finally developing new vector control tools and testing them in the field. All groups also aim to strengthen capacity in malaria-endemic countries on the basis of institutional collaborative arrangements and formal training courses.

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Selected projects at this location:

Stuck L et al. Can school-based distribution be used to maintain coverage of long-lasting insecticide treated bed nets: evidence from a large scale programme in southern Tanzania?. Health Policy Plan. 2017(in press). DOI: 10.1093/heapol/czx028

Ruffing U et al. Community-associated Staphylococcus aureus from sub-saharan Africa and Germany: a cross-sectional geographic correlation study. Sci Rep. 2017;7(1):154. DOI: 10.1038/s41598-017-00214-8

Kozycki C.T et al. False-negative malaria rapid diagnostic tests in Rwanda: impact of Plasmodium falciparum isolates lacking hrp2 and declining malaria transmission. Malar J. 2017;16:123. DOI: 10.1186/s12936-017-1768-1

Dellicour S et al. First-trimester artemisinin derivatives and quinine treatments and the risk of adverse pregnancy outcomes in Africa and Asia: a meta-analysis of observational studies. PLoS Med. 2017;14(5):e1002290. DOI: 10.1371/journal.pmed.1002290

Fola A.A et al. Higher complexity of infection and genetic diversity of Plasmodium vivax than Plasmodium falciparum across all malaria transmission zones of Papua New Guinea. Am J Trop Med Hyg. 2017;96(3):630-641. DOI: 10.4269/ajtmh.16-0716