IGF1 genotype, mean plasma level and breast cancer risk in the Hawaii/Los Angeles multiethnic cohort (Publications)
The insulin-like growth factor 1 gene (IGF1) is a strong candidate gene for a breast cancer susceptibility model. We investigated a dinucleotide repeat 969 bp upstream from the transcription start sit
First clinical trial of purified, irradiated malaria sporozoites in humans (Publications)
Evaluation of: Epstein JE, Tewari K, Lyke KE et al. Live attenuated malaria vaccine designed to protect through hepatic CD8 T cell immunity. Science 334(6055), 475-480 (2011). Purified, irradiated, me
Pyrocoll, an antibiotic, antiparasitic and antitumor compound produced by a novel alkaliphilic streptomyces strain (Publications)
A new secondary metabolite was detected in the culture extract of Streptomyces sp. AK 409 by HPLC-diode-array screening. The metabolite was identified as pyrocoll, which is known to be a constituent o
Antiprotozoal activity of 1-phenethyl-4-aminopiperidine derivatives (Publications)
A series of 44 4-aminopiperidine derivatives was screened in vitro against four protozoan parasites (Trypanosoma brucei rhodesiense, Trypanosoma cruzi, Leishmania donovani, and Plasmodium falciparum).
Identification and characterization of a conserved, stage-specific gene product of <em>Plasmodium falciparum</em> recognized by parasite growth... (Publications)
We have identified a novel conserved protein of Plasmodium falciparum, designated D13, that is stage-specifically expressed in asexual blood stages of the parasite. The predicted open reading frame (O
Nasal nitric oxide measurements to screen children for primary ciliary dyskinesia (Publications)
STUDY OBJECTIVE: To examine the usefulness of exhaled and nasal nitric oxide (NO) measurements to detect primary ciliary dyskinesia (PCD) in children. DESIGN AND METHODS: The study population consiste
Introducing vouchers for malaria prevention in Ghana and Tanzania: context and adoption of innovation in health systems (Publications)
There are striking similarities in health system and other contexts between Tanzania and Ghana that are relevant to the scaling up of continuous delivery of insecticide treated nets (ITNs) for malaria