Mapping of research on maternal health interventions in low- and middle-income countries: a review of 2292 publications between 2000 and 2012 (Publications)
systems strengthening, health promotion; and on five tracer conditions (haemorrhage, hypertension, malaria, HIV and other sexually transmitted infections (STIs)). Following review of 35,078 titles and abstracts [...] More than half the studies were done in sub-Saharan Africa (55.4 %), mostly addressing HIV and malaria. This region had low numbers of publications per hypertension and haemorrhage deaths, though South
Operational challenges to continuous LLIN distribution: a qualitative rapid assessment in four countries (Publications)
BACKGROUND: The World Health Organization recommends that long-lasting insecticidal nets (LLINs) for malaria prevention should be distributed continuously through antenatal care (ANC) and the expanded programme [...] participants were included (23 in Kenya, 13 in Malawi, 18 in Mali and 16 in Rwanda), drawn from malaria programmes, ANC and EPI programmes, government logistics units, and partner organizations. Interviews
Multi-center screening of the Pathogen Box collection for schistosomiasis drug discovery (Publications)
accelerate drug discovery for diseases of poverty, the Medicines for Malaria Venture (MMV) has released box sets of 400 compounds named the Malaria, Pathogen and Stasis Boxes. Here, we screened the Pathogen Box
Modifications and hybrids of 1,2,3,4‑tetrahydropyridinium salts and their antiprotozoal potencies (Publications)
were investigated for their activity against Plasmodium falciparum NF54, a causative organism of Malaria tropica and Trypanosoma brucei rhodesiense, the causative organism of Human African Trypanosomiasis
<em>Plasmodium</em> sensitivity to artemisinins: magic bullets hit elusive targets (Publications)
the genetic basis of laboratory-induced or field-observed altered susceptibility is crucial for malaria control. In this review different models of artemisinins' molecular action are briefly presented
Diseases and Programmes | Swiss TPH (Page)
https://www.swisstph.ch/en/about/scih/diseases-and-programmes
(ESHIA) in Burkina Faso on the use of genetically modified mosquitoes (GMMs) for future malaria control. Target Malaria - a vector control research collaborative based at Imperial College, London - aims to [...] evaluations; and (iii) poverty-related diseases such as Neglected Tropical Diseases, tuberculosis and malaria. From validation to application and health impact assessment We pay particular attention to “access” [...] to develop genetic technologies to modify mosquitoes to ultimately...
Science Publication: SARS-CoV-2 Genomic Surveillance in Africa (Page)
https://www.swisstph.ch/en/science-publication-sars-cov-2-genomic-surveillance-in-africa
set up the Baney Public Health Laboratory as part of the Equatoguinean Malaria Vaccine Initiative to work on the development of malaria vaccines. This laboratory was implemented as early as January 2020 by [...] Africa CDC, WHO AFRO and 300 other institutions across the continent, including Swiss TPH. From Malaria Vaccine Development to SARS-CoV-2 Screening Swiss TPH and partners from Equatorial Guinea contributed
Using observed incidence to calibrate the transmission level of a mathematical model for <em>Plasmodium vivax</em> dynamics including case management... (Publications)
model is used to calculate local reproduction numbers in Panama and identify areas of sustained malaria transmission that should be targeted by control interventions.
Antiprotozoal activity profiling of approved drugs: a starting point toward drug repositioning (Publications)
available to treat diseases such as leishmaniasis, Chagas' disease, human African trypanosomiasis and malaria. Since drug development is lengthy and expensive, a drug repurposing strategy offers an attractive
Aligning new interventions with developing country health systems: target product profiles, presentation, and clinical trial design (Publications)
anticipated use of the intervention in target countries. Examples are provided from research on malaria vaccines that are also applicable to other new public health interventions