Malaria eradication and elimination: views on how to translate a vision into reality (Publications)
deaths due to malaria, there are still an estimated 219 million cases of malaria a year, causing more than half a million deaths. In this forum article, we asked experts working in malaria research and [...] which malaria might eventually be eradicated. Their collective views highlight the challenges and opportunities, and explain how multi-factorial and integrated processes could eventually make malaria eradication
Implementation of the global plan for insecticide resistance management in malaria vectors: progress, challenges and the way forward (Publications)
resistance of malaria vectors to insecticides, particularly to pyrethroids which are widely used in insecticide-treated nets. The Global Plan for Insecticide Resistance Management in malaria vectors (GPIRM) [...] to effective malaria prevention. Aligning efforts and assigning the needed resources will ensure the optimal implementation of GPIRM with the ultimate goal of maintaining effective malaria vector control [...] (GPIRM), released in May 2012, is a collective strategy for the malaria...
Malaria Policy Advisory Committee to the WHO: conclusions and recommendations of seventh biannual meeting (March 2015) (Publications)
reviews or consultations on malaria terminology, malaria in pregnancy, and the feasibility of eradication; as well as updates from the World Health Organization Global Malaria Programme regarding their strategy [...] The Malaria Policy Advisory Committee to the World Health Organization held its seventh meeting in Geneva, Switzerland from 5 to 7 March 2015. This article provides a summary of the discussions, conclusions [...] policy setting processes. Policy statements, position statements, and...
Effective coverage and systems effectiveness for malaria case management in sub-Saharan African countries (Publications)
Scale-up of malaria preventive and control interventions over the last decade resulted in substantial declines in mortality and morbidity from the disease in sub-Saharan Africa and many other parts of [...] infectious reservoir and averting emergence and spread of drug resistance. However many patients with malaria do not access care, providers do not comply with treatment guidelines, and hence, patients do not [...] seeking, provider compliance, adherence, and quality of medication to estimate...
An operational comparative study of quinine and artesunate for the treatment of severe malaria in hospitals and health centres in the Democratic... (Publications)
has the highest number of severe malaria cases in the world. In early 2012, the National Malaria Control Programme (NMCP) changed the policy for treating severe malaria in children and adults from injectable
The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: a meta-analysis of individual patient... (Publications)
d Plasmodium falciparum malaria in Africa. We investigated the impact of different dosing strategies on the efficacy of this combination for the treatment of falciparum malaria. METHODS: Individual patient
Applications and limitations of Centers for Disease Control and Prevention miniature light traps for measuring biting densities of African malaria... (Publications)
BACKGROUND: Measurement of densities of host-seeking malaria vectors is important for estimating levels of disease transmission, for appropriately allocating interventions, and for quantifying their impact [...] methods for their consistency in sampling indoor-feeding mosquitoes belonging to the two major taxa of malaria vectors across Africa, the Anopheles gambiae sensu lato complex and the Anopheles funestus s.l. group [...] easy to deploy on a large scale. Spatial and temporal variation in...
Managing the sick child in the era of declining malaria transmission: development of ALMANACH, an electronic algorithm for appropriate use of... (Publications)
based on a respiratory rate threshold of 50 assessed twice for febrile children 12-59 months; iv) malaria rapid diagnostic test performed for all febrile children. In the absence of identified source of
Distribution of malaria exposure in endemic countries in Africa considering country levels of effective treatment (Publications)
BACKGROUND: Malaria prevalence, clinical incidence, treatment, and transmission rates are dynamically interrelated. Prevalence is often considered a measure of malaria transmission, but treatment of clinical [...] clinical malaria reduces prevalence, and consequently also infectiousness to the mosquito vector and onward transmission. The impact of the frequency of treatment on prevalence in a population is generally [...] generally not considered. This can lead to potential underestimation of ma...