Community-based prevalence of typhoid fever, typhus, brucellosis and malaria among symptomatic individuals in Afar Region, Ethiopia (Publications)
650 suspected individuals for malaria, 16 (2.5%) were found positive for P. falciparum infection. CONCLUSION: In this study, typhoid fever, typhus, brucellosis and malaria were observed among symptomatic [...] scarcity of proper diagnostic tools, febrile illness related symptoms are often misdiagnosed as malaria. Information on causative agents of febrile illness related symptoms among pastoral communities in [...] based cross-sectional survey, we assessed the prevalence of typhoid fever,...
Outdoor malaria transmission risks and social life: a qualitative study in South-Eastern Tanzania (Publications)
BACKGROUND: Behaviour changes in mosquitoes from indoor to outdoor biting result in continuing risk of malaria from outdoor activities, including routine household activities and occasional social and cultural [...] of various social and cultural gatherings that incidentally expose people to mosquito bites and malaria infection. RESULTS: Religious, cultural and social gatherings involving the wider community are conducted [...] work towards elimination. Focusing on single interventions will not...
The promise, problems and pitfalls of mass drug administration for malaria elimination: a qualitative study with scientists and policymakers (Publications)
mass drug administration (MDA). This article explores attitudes towards and perceptions of MDA for malaria elimination among policymakers and leading malariologists. Methods: Thirty-two semistructured interviews [...] with policymakers (n=17) and principal investigators (n=15) selected based on their involvement in malaria prevention, control and elimination in the GMS. Interviews were audio recorded and transcribed for [...] Results: Researchers and policymakers described reluctance and...
Identifying key factors of the transmission dynamics of drug-resistant malaria (Publications)
Development of resistance to malaria treatments remains a great threat to continued malaria burden reduction and elimination. Quantifying the impact of key factors which increase the emergence and spread
Does test-based prescription of evidence-based treatment for malaria improve treatment seeking and satisfaction? Findings of repeated cross-sectional... (Publications)
Introduction: The presumptive treatment of febrile illness with antimalarial medication is becoming less common in low-income and middle-income countries as access to reliable diagnostic tests improve
The candidate blood-stage malaria vaccine P27A induces a robust humoral response in a fast track to the field phase I trial in exposed and non exposed... (Publications)
The present project aimed at evaluating the safety and immunogenicity of P27A peptide vaccine in malaria non-exposed European and exposed African adults. Methods: This study was designed as a staggered [...] GLA-SE (2.5 or 5mug), or control rabies vaccine (Verorab(R)) were administered intramuscularly to 16 malaria non-exposed and 40 exposed subjects on days 0, 28 and 56. Local and systemic adverse events (AEs) [...] an ADCI dependent mechanism. Incidence of AEs and antibody responses were...