Open Malaria : a simulator program for studying malaria epidemiology and the impacts of interventions against malaria [Software] (Publications)
OpenMalaria is an open source C++ program for simulating malaria epidemiology and the impacts on that epidemiology of interventions against malaria. It is based on microsimulations of
MALARIA VACCINE - Safety And Immunogenicity Of Novel Candidate Blood-Stage Malaria Vaccine P27A With Alhydrogel (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/malaria-vaccine-safety-and-immunogenicity-of-novel-candidate-blood-stage-malaria-vaccine-p27a-with-alhydrogel
Further research and optimisation of new malaria vaccines and technologies is ongoing at Swiss TPH. This includes testing of new candidates in Africa such as P27a that was brought in one go from a Phase [...] that the novel adjuvant GLA-SE induces significant cellular immune responses specific for P27a in malaria pre-exposed volunteers.
Early whole blood transcriptional responses to radiation-attenuated <em>Plasmodium falciparum</em> sporozoite vaccination in malaria naive and malaria... (Publications)
radiation-attenuated P. falciparum sporozoites were analysed and compared across malaria-naive adult participants (IMRAS) and malaria-experienced adult participants (BSPZV1). Parasite dose and method of delivery [...] despite stark differences between the two studies, including route of vaccination and status of malaria exposure, responses were identified that were associated with protection after PfRAS vaccination
The effect of community-driven larval source management and house improvement on malaria transmission when added to the standard malaria control... (Publications)
sufficient for malaria elimination. The effects of community-based house improvement (HI) and larval source management (LSM) as supplementary interventions to the Malawi National Malaria Control Programme [...] tion indicated a promising reduction in malaria transmission for the area, but also limited the usefulness of this outcome for measuring differences in malaria transmission among the trial arms. Trial [...] bed net use, neither community-based HI, LSM, nor HI + LSM contributed to further...