Morbidity and nutrition patterns of three nomadic pastoralist communities of Chad (Publications)
diarrhoea occurred more often during the wet season when access to clean drinking water was precarious. Malaria was only rarely clinically diagnosed among Arabs during the dry season, whereas Fulani, who stayed
The epidemiology of multiple <em>Plasmodium falciparum</em> infections. 10. Effect of insecticide-treated bed nets on the dynamics of multiple... (Publications)
areas of high P. falciparum endemicity, ITNs have little effect on the establishment of chronic malaria infection.
Recours aux soins et utilisation des services de santé à Nouakchott (Mauritanie): inégalités spatiales ou pesanteurs sociales? (Publications)
or weight loss) seen to suggest more serious diseases, such as tuberculosis, meningitis or severe malaria. Geographic accessibility of health services was relatively good (70 %). It was the economic, so
Discovery of dual function acridones as a new antimalarial chemotype (Publications)
resistance, and both are undesirable in effective long-term strategies against multi-drug-resistant malaria. Haem remains an immutable and vulnerable target, because it is not parasite-encoded and its det
Setting priorities for knowledge translation of Cochrane reviews for health equity: evidence for equity (Publications)
with high burdens of disease globally, were selected for the pilot: diabetes/obesity, HIV/AIDS, malaria, nutrition, and mental health/depression. For each topic area, a "stakeholder panel" was assembled
Ancistrobrevines E-J and related naphthylisoquinoline alkaloids from the West African liana <em>Ancistrocladus abbreviatus</em> with inhibitory... (Publications)
e compounds. Some of the alkaloids of A. abbreviatus exhibited promising activities against the malaria parasite Plasmodium falciparum and PANC-1 human pancreatic cancer cells.
Effect of insecticide-treated bed nets on the dynamics of multiple <em>Plasmodium falciparum</em> infections (Publications)
areas of high P. falciparum endemicity, ITNs have little effect on the establishment of chronic malaria infection.
The antiprotozoal activity of methylated flavonoids from <em>Ageratum conyzoides</em> L (Publications)
against Leishmania donovani (Kala-Azar, IC(50)=3.4 microg/mL) as well as Plasmodium falciparum (Malaria tropica, IC(50)=8.0 microg/mL). In the current study, we sought for potentially active constituents
First-in-man safety and pharmacokinetics of synthetic ozonide OZ439 demonstrates an improved exposure profile relative to other peroxide antimalarials (Publications)
progression to Phase 2a proof-of concept studies in the target population of acute uncomplicated malaria
<em>In vitro</em> and<em> in vivo</em> activity of Solithromycin (CEM-101) against <em>Plasmodium</em> species (Publications)
the same dose required for artesunate or chloroquine to achieve 100% cure rates in this rodent malaria model. These promising in vitro and in vivo data support further investigations into the development