Antigenicity and immunogenicity of a novel chimeric peptide antigen based on the <em>P. vivax</em> circumsporozoite protein (Publications)
indicated that the chimeric peptide is recognized by a high proportion (60-70%) of residents of malaria-endemic areas. Peptides formulated with either GLA-SE or Montanide ISA51 adjuvants induced stronger
Validation of <em>Plasmodium falciparum</em> dUTPase as the target of 5'-tritylated deoxyuridine analogues with anti-malarial activity (Publications)
BACKGROUND: Malaria remains as a major global problem, being one of the infectious diseases that engender highest mortality across the world. Due to the appearance of resistance and the lack of an effective
Screening open access compound libraries and repurposing drugs to identify and characterize new molecules active against schistosomiasis and other... (Publications)
Far from the baneful impact of the so-called “big three” (HIV/AIDS, tuberculosis and malaria), schistosomiasis and other worm infections, such as the soil-transmitted helminths (STH) for example, have [...] each, both compiled and provided by the non-profit product development partnership Medicines for Malaria Venture (MMV). One library, the Pathogen Box, was composed of drug-like molecules with already-known
Monitoring <em>Plasmodium falciparum</em> and <em>Plasmodium vivax</em> using microsatellite markers indicates limited changes in population structure... (Publications)
transmission declines. Here we describe the first population genetic analysis of the major human malaria parasites, Plasmodium falciparum (Pf) and Plasmodium vivax (Pv) following nationwide distribution
Efficacy of ICON(R) Maxx in the laboratory and against insecticide-resistant <em>Anopheles gambiae</em> in central Côte d'Ivoire (Publications)
reduction in blood-feeding rates; features that are likely to have a positive impact in reducing malaria transmission. The WHO cone test may not always be a good proxy for predicting product performance
Paediatric referrals in rural Tanzania: the Kilombero District Study - a case series (Publications)
dispensaries. Almost half of the referrals (48%) took 2 or more days to arrive at the hospital. Severe malaria and anaemia were the leading diagnoses in referred children, together accounting for a total of 70%
Comparative performance of the Mbita trap, CDC light trap and the human landing catch in the sampling of <em>Anopheles arabiensis</em>, <em>An.... (Publications)
BACKGROUND: Mosquitoes sampling is an important component in malaria control. However, most of the methods used have several shortcomings and hence there is a need to develop and calibrate new methods
Systematic review of the entomological impact of insecticide-treated nets evaluated using experimental hut trials in Africa (Publications)
Africa, diminishing the efficacy of insecticide-treated nets (ITNs) – the primary tool for preventing malaria. The entomological efficacy of indoor vector control interventions can be measured in experimental
Global health initiative investments and health systems strengthening: a content analysis of global fund investments (Publications)
subset of 52 of the 139 grants funded in Round 8 of the Global Fund to Fight AIDS, Tuberculosis and Malaria (totalling approximately US$1 billion). RESULTS: According to the analysis, 37% (US$ 362 million)
The antiprotozoal activity of sixteen asteraceae species native to Sudan and bioactivity-guided isolation of xanthanolides from <em>Xanthium... (Publications)
against T. CRUZI (Chagas disease), LEISHMANIA DONOVANI (Kala-Azar) as well as PLASMODIUM FALCIPARUM (Malaria tropica). Bioactivity-guided fractionation resulted in the isolation of four bioactive sesquiterpene