Potential for reduction of burden and local elimination of malaria by reducing <em>Plasmodium falciparum</em> malaria transmission: a mathematical... (Publications)
a mathematical model of the transmission of Plasmodium falciparum malaria to explore the potential effect on case incidence and malaria mortality rates from 2015 to 2030 of five different intervention [...] BACKGROUND: Rapid declines in malaria prevalence, cases, and deaths have been achieved globally during the past 15 years because of improved access to first-line treatment and vector control. We aimed [...] with a switch from quinine to injectable artesunate for management of severe disease...
Relationship between child survival and malaria transmission: an analysis of the malaria transmission intensity and mortality burden across Africa... (Publications)
relationship between malaria mortality and levels of transmission is unclear. Due to methodological limitations, earlier efforts to assess the linkage have lead to inconclusive results. The malaria transmission [...] assessing the malaria transmission-mortality relation involves more than the knowledge on the performance of interventions and control measures. This relation depends on the levels of malaria endemicity and [...] age and insecticide-treated nets (ITNs), were fitted to assess the...
Disparities of <em>Plasmodium falciparum</em> infection, malaria-related morbidity and access to malaria prevention and treatment among school-aged... (Publications)
There is limited knowledge on the malaria burden of school-aged children in Cote d'Ivoire. The aim of this study was to assess Plasmodium falciparum infection, malaria-related morbidity, use of preventive [...] preventive measures and treatment against malaria, and physical access to health structures among school-aged children across Cote d'Ivoire. METHODS: A national, cross-sectional study was designed, consisting [...] were interviewed to determine household socioeconomic status,...
The public health impact of malaria vaccine RTS,S in malaria endemic Africa: country-specific predictions using 18 month follow-up Phase III data and... (Publications)
control programs, assuming continuation of current levels of malaria exposure and of health system performance, will potentially avert 100-580 malaria deaths and 45,000 to 80,000 clinical episodes per 100,000 [...] BACKGROUND: The RTS,S/AS01 malaria vaccine candidate recently completed Phase III trials in 11 African sites. Recommendations for its deployment will partly depend on predictions of public health impact [...] estimated by Bayesian fitting of these models to the site- and time-specific...
Malaria risk in Nigeria: Bayesian geostatistical modelling of 2010 malaria indicator survey data (Publications)
2010, the National Malaria Control Programme with the support of Roll Back Malaria partners implemented a nationally representative Malaria Indicator Survey (MIS), which assembled malaria burden and control [...] ic predictors of malaria risk. The population adjusted risk estimates ranges from 6.46% in Lagos state to 43.33% in Borno. Interventions appear to not have important effect on malaria risk. The odds of [...] and living in rural areas increases the odds of testing positive to malaria...
Vector composition, abundance, biting patterns and malaria transmission intensity in Madang, Papua New Guinea: assessment after 7 years of an... (Publications)
BACKGROUND: A malaria control programme based on distribution of long-lasting insecticidal bed nets (LLINs) and artemisinin combination therapy began in Papua New Guinea in 2009. After implementation of [...] of the programme, substantial reductions in vector abundance and malaria transmission intensity occurred. The research reported here investigated whether these reductions remained after seven years of [...] Anopheles per screen-night and 2.2-31.1 Anopheles per person-night), and spatially...
Closing the malaria prevention gap: measuring and characterizing human behavioral drivers of persistent malaria transmission in Sub-Saharan Africa (Publications)
two-thirds of the reduction in malaria burden over the past two decades. However, progress has begun to stall in recent years highlighting the importance of enhanced malaria prevention efforts. The aim of [...] Malaria kills a person nearly every minute, most often a child under the age of five. While endemic in many parts of the world, a disproportionate burden of cases and deaths are borne by people living [...] living in sub-Saharan Africa. Malaria is transmitted by the female Anopheles...