Open Malaria : a simulator program for studying malaria epidemiology and the impacts of interventions against malaria [Software] (Publications)
OpenMalaria is an open source C++ program for simulating malaria epidemiology and the impacts on that epidemiology of interventions against malaria. It is based on microsimulations of
Early whole blood transcriptional responses to radiation-attenuated <em>Plasmodium falciparum</em> sporozoite vaccination in malaria naive and malaria... (Publications)
radiation-attenuated P. falciparum sporozoites were analysed and compared across malaria-naive adult participants (IMRAS) and malaria-experienced adult participants (BSPZV1). Parasite dose and method of delivery [...] despite stark differences between the two studies, including route of vaccination and status of malaria exposure, responses were identified that were associated with protection after PfRAS vaccination
The effect of community-driven larval source management and house improvement on malaria transmission when added to the standard malaria control... (Publications)
sufficient for malaria elimination. The effects of community-based house improvement (HI) and larval source management (LSM) as supplementary interventions to the Malawi National Malaria Control Programme [...] tion indicated a promising reduction in malaria transmission for the area, but also limited the usefulness of this outcome for measuring differences in malaria transmission among the trial arms. Trial [...] bed net use, neither community-based HI, LSM, nor HI + LSM contributed to further...
Evaluation of seasonal malaria chemoprevention in two areas of intense seasonal malaria transmission: secondary analysis of a household-randomised,... (Publications)
s 0.13 (95% CI: 0.08, 0.20), P < 0.001 for malaria hospitalisations and deaths from malaria and 0.21 (95% CI 0.20, 0.23), P < 0.001 for uncomplicated malaria, indicating protective efficacy of 87.4% (95% [...] BACKGROUND: Seasonal malaria chemoprevention (SMC) is now widely deployed in the Sahel, including several countries that are major contributors to the global burden of malaria. Consequently, it is important [...] coverage and high adherence to SMC, the incidence of hospitalisations or...