Open Malaria : a simulator program for studying malaria epidemiology and the impacts of interventions against malaria [Software] (Publications)
OpenMalaria is an open source C++ program for simulating malaria epidemiology and the impacts on that epidemiology of interventions against malaria. It is based on microsimulations of
Patterns of human exposure to malaria vectors in Zanzibar and implications for malaria elimination efforts (Publications)
study for malaria elimination. The islands have experienced a dramatic reduction in malaria burden since the introduction of effective vector control interventions and case management. Malaria prevalence [...] sleep. Supplemental interventions targeting outdoor exposure to malaria vectors, and groups that may be at increased risk of exposure to malaria vectors, should be explored. [...] for elimination. METHODS: To better understand factors that may contribute to remaining low-level malaria...
Intravenous artesunate reduces parasite clearance time, duration of intensive care and hospital treatment in patients with severe malaria in Europe:... (Publications)
Intravenous artesunate improves survival in severe malaria, but clinical trial data from non-endemic countries are scarce. The TropNet severe malaria database was analyzed to compare outcomes of artesunate [...] clearance time, duration of ICU- and hospital treatment in European patients with imported severe malaria
Impact of malaria pre-exposure on anti-parasite cellular and humoral immune responses after controlled human malaria infection (Publications)
understand the effect of previous malaria exposure on anti-parasite immune responses is important for developing successful immunization strategies. Controlled human malaria infections (CHMI) using cryopreserved [...] sporozoites provide a unique opportunity to study differences in acquisition or re-call of anti-malaria immune responses in individuals from different transmission settings and genetic backgrounds. In [...] In this study, we compared anti-parasite humoral and cellular immune...