Modelling the epidemiological impact of intermittent preventive treatment against malaria in infants (Publications)
preventive treatment against malaria in infants (IPTi) using sulphadoxine-pyrimethamine (SP) have shown a positive, albeit variable, protective efficacy against clinical malaria episodes. The impact of IPTi [...] periods. The predicted cumulative benefits were proportionately slightly greater for severe malaria episodes and malaria-attributable mortality than for acute episodes in the settings modelled. Modest increased [...] mortality. METHODS/PRINCIPAL FINDINGS: We used a comprehensive,...
Epidemiology and clinical features of vivax malaria imported to Europe: sentinel surveillance data from TropNetEurop (Publications)
Plasmodium vivax is the second most common species among malaria patients diagnosed in Europe, but epidemiological and clinical data on imported P. vivax malaria are limited. The TropNetEurop surveillance network [...] network has monitored the importation of vivax malaria into Europe since 1999. OBJECTIVES: To present epidemiological and clinical data on imported P. vivax malaria collected at European level. MATERIAL AND [...] AND METHODS: Data of primary cases of P. vivax malaria reported...
What should vaccine developers ask? Simulation of the effectiveness of malaria vaccines (Publications)
effects of malaria vaccines on malaria transmission, morbidity and mortality. The models are fitted and simulations obtained via volunteer computing. We consider a range of endemic malaria settings with [...] BACKGROUND: A number of different malaria vaccine candidates are currently in pre-clinical or clinical development. Even though they vary greatly in their characteristics, it is unlikely that any of them [...] them will provide long-lasting sterilizing immunity against the malaria parasite....
Malaria: a major health problem within an oil palm plantation around Popondetta, Papua New Guinea (Publications)
023 malaria cases were diagnosed at the aid posts and malaria accounted for 30-40% of all clinical cases. Of the malaria cases, 13-20% were HOP employees. On average, an employee sick with malaria was [...] BACKGROUND: For companies operating in malaria endemic countries, malaria represents a substantial risk to workers and their dependants, and can lead to significantly reduced worker productivity. This [...] 2006. Sleeping outside of the house did not increase the risk of a malaria infection,...
Potential benefits, limitations and target product-profiles of odor-baited mosquito traps for malaria control in Africa (Publications)
as suitable technologies for controlling malaria and other mosquito-borne diseases. We investigated the potential benefits of such traps for preventing malaria transmission in Africa and the essential [...] users and non-users of insecticide-treated nets (ITNs), currently the primary malaria prevention method. We determined that malaria transmission declines as trap coverage (proportion of total availability of [...] match the impact of 50% community-wide ITN coverage. If such traps are used to...
Estimating the burden of malaria: the need for improved surveillance (Publications)
the importance of using complementary methods to estimate the burden of malaria and call for a renewed focus on efficient malaria surveillance
Development of behaviour change communication strategy for a vaccination-linked malaria control tool in southern Tanzania (Publications)
preventive treatment of malaria in infants (IPTi) using sulphadoxine-pyrimethamine and linked to the expanded programme on immunization (EPI) is a promising strategy for malaria control in young children [...] after the injections. Sulphadoxine-pyrimethamine was widely used for malaria treatment and intermittent preventive treatment of malaria in pregnancy, despite widespread rumours of adverse reactions based [...] survey were used to investigate communities' and providers' knowledge and...
Frequency of malaria and glucose-6-phosphate dehydrogenase deficiency in Tajikistan (Publications)
high malaria risk with high current incidence rates, where malaria control and prevention measures should be taken at all stages of the transmission cycle; (ii) zones at relatively high malaria risk with [...] with low current incidence rates, where malaria prevention measures are recommended; and (iii) zones at intermediate or low malaria risk with low current incidence rates where no particular measures appear [...] indicates that malaria is a serious health issue in specific regions of...
Implementation of an insecticide-treated net subsidy scheme under a public-private partnership for malaria control in Tanzania--challenges in... (Publications)
commitments from organizations such as the Global Fund for HIV/AIDS, Tuberculosis and Malaria (GFATM), the President's Malaria Initiative and the World Bank Booster programme. METHODS: The case study uses the [...] BACKGROUND: In the past decade there has been increasing visibility of malaria control efforts at the national and international levels. The factors that have enhanced this scenario are the availability [...] implementation of a public-private partnership approach embarked upon by the...