Functional and structural similarity of Vgamma9Vdelta2 T cells in humans and Aotus monkeys, a primate infection model for <em>Plasmodium falciparum... (Publications)
gammadelta T cells are implicated to play crucial roles during early immune responses to pathogens. A subset of human gammadelta T cells carrying the Vgamma9Vdelta2 TCR recognize small, phosphorylated
First clinical trial of purified, irradiated malaria sporozoites in humans (Publications)
Evaluation of: Epstein JE, Tewari K, Lyke KE et al. Live attenuated malaria vaccine designed to protect through hepatic CD8 T cell immunity. Science 334(6055), 475-480 (2011). Purified, irradiated, me [...] route in humans are warranted to fully explore the potential of purified, attenuated sporozoites for malaria vaccine development
Introducing vouchers for malaria prevention in Ghana and Tanzania: context and adoption of innovation in health systems (Publications)
that are relevant to the scaling up of continuous delivery of insecticide treated nets (ITNs) for malaria prevention. However, specific contextual factors of relevance to ITN delivery have led implementation
Determining important parameters in the spread of malaria through the sensitivity analysis of a mathematical model (Publications)
We perform sensitivity analyses on a mathematical model of malaria transmission to determine the relative importance of model parameters to disease transmission and prevalence. We compile two sets of baseline [...] as the prompt diagnosis and treatment of infectious individuals) can be successful in controlling malaria
Pharmacotherapy, vaccines and malaria advice for HIV-infected travellers (Publications)
acquired during travel may be more frequent or severe. Challenges include the best options for malaria chemoprophylaxis, standby treatment and medical follow-up of the increasing number of HIV-infected