Unit | Clinical Research

TB clinic, Bagamoyo, Tanzania

The aim of the Clinical Research Unit (CRU) is to design, conduct and report clinical research studies at Swiss TPH and partner institutions and to provide support for Swiss TPH scientists for clinical questions.

Research

The CRU aims to strengthen high standard clinical research at Swiss TPH. The CRU conducts clinical research in the areas of malaria, febrile illnesses, tuberculosis, HIV/AIDS, neglected tropical diseases, and emerging non-communicable chronic diseases in low- and middle-income countries in collaboration with numerous partner institutes.

Support

The members of the CRU, who have a wide range of expertise in clinical research, provide scientific support with regard to clinical and methodological aspects during the development of research proposals and protocols. The clinical support is part of the Project and Grant Service at Swiss TPH. All proposals and protocols for clinical trials are reviewed by the CRU. Observational clinical studies may also be reviewed if desired by the investigators.

Boeree M.J et al. High-dose rifampicin, moxifloxacin, and SQ109 for treating tuberculosis: a multi-arm, multi-stage randomised controlled trial. Lancet Infect Dis. 2017;17(1):39-49. DOI: 10.1016/S1473-3099(16)30274-2

Boillat-Blanco N et al. Association between tuberculosis, diabetes and 25 hydroxyvitamin D in Tanzania: a longitudinal case control study. BMC Infect Dis. 2016;16:626. DOI: 10.1186/s12879-016-1960-x

Reither K. Aufbau von Kapizitäten für klinische Tuberkulosesstudien: das Schweiz Tansania Modell. In: Reither K, ed. Deutsches Zentralkomitee zur Bekämpfung der Tuberkulose: 39. Informationsbericht, 26-31. Berlin: DZK, 2016

Petrone L et al. Blood and urine inducible protein 10 as potential markers of disease activity. Int J Tuberc Lung Dis. 2016;20(11):1554-1561. DOI: 10.5588/ijtld.16.0342

Bholla M et al. Evaluation of Xpert® MTB/RIF and Ustar EasyNATTM TB IAD for diagnosis of TB lymphadenitis of children in Tanzania. BMC Infect Dis. 2016;16:246. DOI: 10.1186/s12879-016-1578-z