Unit | Clinical Research

TB clinic, Bagamoyo, Tanzania

The aim of the Clinical Research Unit (CRU) is to design, conduct and report clinical research studies at Swiss TPH and partner institutions and to provide support for Swiss TPH scientists for clinical questions.


The CRU aims to strengthen high standard clinical research at Swiss TPH. The CRU conducts clinical research in the areas of malaria, febrile illnesses, tuberculosis, HIV/AIDS, neglected tropical diseases, and emerging non-communicable chronic diseases in low- and middle-income countries in collaboration with numerous partner institutes.


The members of the CRU, who have a wide range of expertise in clinical research, provide scientific support with regard to clinical and methodological aspects during the development of research proposals and protocols. The clinical support is part of the Project and Grant Service at Swiss TPH. All proposals and protocols for clinical trials are reviewed by the CRU. Observational clinical studies may also be reviewed if desired by the investigators.

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Mhimbira F et al. Prevalence and clinical relevance of helminth co-infections among tuberculosis patients in urban Tanzania. PLoS Negl Trop Dis. 2017;11(2):e0005342. DOI: 10.1371/journal.pntd.0005342

Said K et al. Tuberculosis among HIV-infected population: incidence and risk factors in rural Tanzania. Afr Health Sci. 2017;17(1):208-215

Boillat-Blanco N et al. Association between tuberculosis, diabetes and 25 hydroxyvitamin D in Tanzania: a longitudinal case control study. BMC Infect Dis. 2016;16:626. DOI: 10.1186/s12879-016-1960-x

Reither K. Aufbau von Kapizitäten für klinische Tuberkulosesstudien: das Schweiz-Tansania Modell. In: Reither K, ed. Deutsches Zentralkomitee zur Bekämpfung der Tuberkulose: 39. Informationsbericht, 26-31. Berlin: DZK, 2016