Unit | Clinical Research

TB clinic, Bagamoyo, Tanzania

The aim of the Clinical Research Unit (CRU) is to design, conduct and report clinical research studies at Swiss TPH and partner institutions and to provide support for Swiss TPH scientists for clinical questions.


The CRU aims to strengthen high standard clinical research at Swiss TPH. The CRU conducts clinical research in the areas of malaria, febrile illnesses, tuberculosis, HIV/AIDS, neglected tropical diseases, and emerging non-communicable chronic diseases in low- and middle-income countries in collaboration with numerous partner institutes.


The members of the CRU, who have a wide range of expertise in clinical research, provide scientific support with regard to clinical and methodological aspects during the development of research proposals and protocols. The clinical support is part of the Project and Grant Service at Swiss TPH. All proposals and protocols for clinical trials are reviewed by the CRU. Observational clinical studies may also be reviewed if desired by the investigators.

Zumla A et al. Host-directed therapies for infectious diseases: current status, recent progress, and future prospects. Lancet Infect Dis. 2016;16(4):e47-63. DOI: 10.1016/S1473-3099(16)00078-5

Zumla A, Maeurer M, Host-Directed Therapies Network HDT-NET Consortium. Host-directed therapies for tackling multi-drug resistant TB - learning from the Pasteur-Bechamp debates. Clin Infect Dis. 2015;61(9):1432-1438. DOI: 10.1093/cid/civ631

Zumla A et al. Towards host-directed therapies for tuberculosis [Comment]. Nat Rev Drug Discov. 2015;14(8):511-512. DOI: 10.1038/nrd4696